| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50370375 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_414989 (CHEMBL909478) |
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| Ki | 0.7±n/a nM |
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| Citation |  Rosenström, U; Sköld, C; Lindeberg, G; Botros, M; Nyberg, F; Karlén, A; Hallberg, A Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors. J Med Chem49:6133-7 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41201.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Angiotensin II, central 0 0::P50052 |
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| Residue: | 363 |
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| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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| BDBM50370375 |
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| n/a |
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| Name | BDBM50370375 |
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| Synonyms: | CHEMBL268815 |
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| Type | Small organic molecule |
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| Emp. Form. | C53H74N12O12 |
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| Mol. Mass. | 1071.2279 |
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| SMILES | [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#7])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |
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| Structure | 
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