| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA polymerase beta |
|---|
| Ligand | BDBM50250348 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_528872 (CHEMBL978545) |
|---|
| IC50 | 22000±n/a nM |
|---|
| Citation |  Sun, DA; Starck, SR; Locke, EP; Hecht, SM DNA polymerase beta inhibitors from Sandoricum koetjape. J Nat Prod62:1110-3 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA polymerase beta |
|---|
| Name: | DNA polymerase beta |
|---|
| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38334.34 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1361926 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
|
|
|
|---|
| BDBM50250348 |
|---|
| n/a |
|---|
| Name | BDBM50250348 |
|---|
| Synonyms: | 3-oxo-olean-12-en-29-oic acid | 3-oxoolean-12-en-29-oic acid | CHEMBL491702 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H46O3 |
|---|
| Mol. Mass. | 454.6844 |
|---|
| SMILES | CC1(C)[C@@H]2CC[C@]3(C)[C@H](CC=C4[C@@H]5C[C@@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O)[C@@]2(C)CCC1=O |r,t:10| |
|---|
| Structure | 
|
|---|
Search and Browse
