Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 mg... | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 m... | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSA | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSA | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 60 mins | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50250362 (3-Oximo-olean-12-en-29-oic acid | CHEMBL490347) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50250352 (3,4-seco-olean-4(23),12-diene-3,30-dioic acid | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50250348 (3-oxo-olean-12-en-29-oic acid | 3-oxoolean-12-en-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 60 mins in presence of 0.1 mg/mL BSA | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50250360 (3-benzyloximo-olean-12-en-29-oic acid | CHEMBL4557...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50250349 (3alpha-hydroxyolean-12-en-29-oic acid | CHEMBL4905...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50250361 (3-methyloximo-olean-12-en-29-oic acid | CHEMBL5241...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Charlottesville Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta | J Nat Prod 62: 1110-3 (1999) Article DOI: 10.1021/np990104r BindingDB Entry DOI: 10.7270/Q2C8293M | |||||||||||
More data for this Ligand-Target Pair |