| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50250360 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_528872 (CHEMBL978545) |
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| IC50 | 35000±n/a nM |
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| Citation |  Sun, DA; Starck, SR; Locke, EP; Hecht, SM DNA polymerase beta inhibitors from Sandoricum koetjape. J Nat Prod62:1110-3 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38334.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1361926 |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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| BDBM50250360 |
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| n/a |
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| Name | BDBM50250360 |
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| Synonyms: | 3-benzyloximo-olean-12-en-29-oic acid | CHEMBL455762 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H53NO3 |
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| Mol. Mass. | 559.8216 |
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| SMILES | C[C@]12CC[C@](C)(C[C@H]1C1=CC[C@@H]3[C@@]4(C)CC\C(=N\OCc5ccccc5)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2)C(O)=O |r,t:9| |
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| Structure | 
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