| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50259746 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_528821 (CHEMBL977663) |
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| IC50 | 47600±n/a nM |
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| Citation |  Deng, S; Chen, SN; Yao, P; Nikolic, D; van Breemen, RB; Bolton, JL; Fong, HH; Farnsworth, NR; Pauli, GF Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. J Nat Prod69:536-41 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50259746 |
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| n/a |
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| Name | BDBM50259746 |
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| Synonyms: | (4-Hydroxyphenyl)ethyl trans-ferulate | CHEMBL481245 | p-Hydroxyphenethyl trans-ferulate (18) | p-hydroxyphenethyl trans-ferulate |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18O5 |
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| Mol. Mass. | 314.3325 |
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| SMILES | COc1cc(\C=C\C(=O)OCCc2ccc(O)cc2)ccc1O |
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| Structure | 
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