| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50251133 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_534562 (CHEMBL988123) |
|---|
| IC50 | 237±n/a nM |
|---|
| Citation |  Song, KS; Lee, SH; Chun, HJ; Kim, JY; Jung, ME; Ahn, K; Kim, SU; Kim, J; Lee, J Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands. Bioorg Med Chem16:4035-51 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52856.55 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P20272 |
|---|
| Residue: | 473 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50251133 |
|---|
| n/a |
|---|
| Name | BDBM50251133 |
|---|
| Synonyms: | 4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-tert-butylpiperazine-1-carboxamide | CHEMBL463846 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27BrClN3O |
|---|
| Mol. Mass. | 464.826 |
|---|
| SMILES | CC(C)(C)NC(=O)N1CCN(CC1)C(c1ccc(Br)cc1)c1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
