| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 2 |
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| Ligand | BDBM50271765 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_556426 (CHEMBL955643) |
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| IC50 | 8.9±n/a nM |
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| Citation |  Fells, JI; Tsukahara, R; Fujiwara, Y; Liu, J; Perygin, DH; Osborne, DA; Tigyi, G; Parrill, AL Identification of non-lipid LPA3 antagonists by virtual screening. Bioorg Med Chem16:6207-17 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 2 |
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| Name: | Lysophosphatidic acid receptor 2 |
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| Synonyms: | EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39103.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1451385 |
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| Residue: | 351 |
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| Sequence: | MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
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| BDBM50271765 |
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| n/a |
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| Name | BDBM50271765 |
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| Synonyms: | 3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acid | 4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylene))bis(azanediyl)bis(4-oxobut-2-enoic acid) | CHEMBL482498 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20N2O8 |
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| Mol. Mass. | 488.4456 |
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| SMILES | OC(=O)\C=C\C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)\C=C\C(O)=O)cc3)c2)cc1 |
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| Structure | 
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