| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50262449 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_514032 (CHEMBL976347) |
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| EC50 | >2000±n/a nM |
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| Citation |  DiMauro, EF; Buchanan, JL; Cheng, A; Emkey, R; Hitchcock, SA; Huang, L; Huang, MY; Janosky, B; Lee, JH; Li, X; Martin, MW; Tomlinson, SA; White, RD; Zheng, XM; Patel, VF; Fremeau, RT Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2. Bioorg Med Chem Lett18:4267-74 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50262449 |
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| n/a |
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| Name | BDBM50262449 |
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| Synonyms: | CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-2-methylbutan-2-yl)quinolin-3-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20ClFN4O |
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| Mol. Mass. | 410.872 |
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| SMILES | CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1 |
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| Structure | 
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