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TargetHydroxycarboxylic acid receptor 2
LigandBDBM50273099
Substrate/Competitorn/a
Meas. Tech.ChEMBL_509905
EC50 1080±n/a nM
Citation Semple GSkinner PJGharbaoui TShin YJJung JKCherrier MCWebb PJTamura SYBoatman PDSage CRSchrader TOChen RColletti SLTata JRWaters MGCheng KTaggart AKCai TQCarballo-Jane EBehan DPConnolly DTRichman JG 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice. J Med Chem 51:5101-8 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Hydroxycarboxylic acid receptor 2
Name:Hydroxycarboxylic acid receptor 2
Synonyms:HM74 nicotinic acid GPCR
Type:PROTEIN
Mol. Mass.:41418.01
Organism:Mus musculus
Description:ChEMBL_820676
Residue:360
Sequence:
MSKSDHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSR
IFLFNLAVADFLLIICLPFLTDNYVHNWDWRFGGIPCRVMLFMLAMNRQGSIIFLTVVAV
DRYFRVVHPHHFLNKISNRTAAIISCFLWGLTIGLTVHLLYTNMMTKNGEAYLCSSFSIC
YNFRWHDAMFLLEFFLPLAIILFCSGRIIWSLRQRQMDRHAKIKRAINFIMVVAIVFIIC
FLPSVAVRIRIFWLLYKYNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPN
FFSTCINRCLRKKTLGEPDNNRSTSVELTGDPSTTRSIPGALMADPSEPGSPPYLASTSR
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  Blast E-value cutoff:
BDBM50273099
n/a
NameBDBM50273099
Synonyms:3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole | 3-(2H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole | CHEMBL456145 | MK-0354
TypeSmall organic molecule
Emp. Form.C7H8N6
Mol. Mass.176.1786
SMILESC1Cc2[nH]nc(c2C1)-c1nnn[nH]1
Structure
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