| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17B |
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| Ligand | BDBM17015 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537072 (CHEMBL986221) |
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| Kd | 353±n/a nM |
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| Citation |  Bamborough, P; Drewry, D; Harper, G; Smith, GK; Schneider, K Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem51:7898-914 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 17B |
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| Name: | Serine/threonine-protein kinase 17B |
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| Synonyms: | DRAK2 | ST17B_HUMAN | STK17B | Serine/threonine-protein kinase 17B | Serine/threonine-protein kinase 17B (STK17B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42332.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O94768 |
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| Residue: | 372 |
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| Sequence: | MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
PNPHELVSDLLC
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| BDBM17015 |
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| n/a |
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| Name | BDBM17015 |
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| Synonyms: | (3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one | CHEMBL86755 | Indolinone based inhibitor, 1 | Oxindole I |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10N2O |
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| Mol. Mass. | 210.2313 |
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| SMILES | O=C1Nc2ccccc2\C1=C\c1ccc[nH]1 |
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| Structure | 
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