| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50246925 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_561007 (CHEMBL1015247) |
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| Ki | >10000±n/a nM |
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| Citation |  Yea, CM; Allan, CE; Ashworth, DM; Barnett, J; Baxter, AJ; Broadbridge, JD; Franklin, RJ; Hampton, SL; Hudson, P; Horton, JA; Jenkins, PD; Penson, AM; Pitt, GR; Rivière, P; Robson, PA; Rooker, DP; Semple, G; Sheppard, A; Haigh, RM; Roe, MB New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists. J Med Chem51:8124-34 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50246925 |
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| n/a |
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| Name | BDBM50246925 |
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| Synonyms: | 1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine | CHEMBL455699 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25F2N3O2 |
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| Mol. Mass. | 449.4924 |
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| SMILES | Cc1cc(ccc1CNC(=O)Nc1c(F)cccc1F)C(=O)N1CCCCc2ccccc12 |
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| Structure | 
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