Compile Data Set for Download or QSAR

Found 576 hits with Last Name = 'allan' and Initial = 'ce'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50246925 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methyl...) Show SMILES Cc1cc(ccc1CNC(=O)Nc1c(F)cccc1F)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C26H25F2N3O2/c1-17-15-19(25(32)31-14-5-4-8-18-7-2-3-11-23(18)31)12-13-20(17)16-29-26(33)30-24-21(27)9-6-10-22(24)28/h2-3,6-7,9-13,15H,4-5,8,14,16H2,1H3,(H2,29,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Binding affinity to human vasopressin V2 receptor expressed in HEK293 cells by radioligand binding assay				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50246575 (1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...) Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12 |r| Show InChI InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Binding affinity to human vasopressin V2 receptor expressed in HEK293 cells by radioligand binding assay				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50246925 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methyl...) Show SMILES Cc1cc(ccc1CNC(=O)Nc1c(F)cccc1F)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C26H25F2N3O2/c1-17-15-19(25(32)31-14-5-4-8-18-7-2-3-11-23(18)31)12-13-20(17)16-29-26(33)30-24-21(27)9-6-10-22(24)28/h2-3,6-7,9-13,15H,4-5,8,14,16H2,1H3,(H2,29,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Binding affinity to oxytocin receptor (unknown origin)				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50246575 (1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-y...) Show SMILES CN(C)C(=O)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12 |r| Show InChI InChI=1S/C27H34N4O3/c1-19-17-21(25(32)30-15-7-6-10-20-9-4-5-11-23(20)30)13-14-22(19)18-28-27(34)31-16-8-12-24(31)26(33)29(2)3/h4-5,9,11,13-14,17,24H,6-8,10,12,15-16,18H2,1-3H3,(H,28,34)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Binding affinity to oxytocin receptor (unknown origin)				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair
Oxytocin receptor (Homo sapiens (Human))	BDBM50246890 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]benzoyl)-...) Show SMILES Fc1cccc(F)c1NC(=O)NCc1ccc(cc1)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C25H23F2N3O2/c26-20-8-5-9-21(27)23(20)29-25(32)28-16-17-11-13-19(14-12-17)24(31)30-15-4-3-7-18-6-1-2-10-22(18)30/h1-2,5-6,8-14H,3-4,7,15-16H2,(H2,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Binding affinity to oxytocin receptor (unknown origin)				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187100 (US9670157, 114 3-Methyl-1-[4-(4-methyl-pyrazol-1-y...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4c(C)cc(CN)cc4C)c(C)n3)cc2)c1 Show InChI InChI=1S/C27H32N6O/c1-18-12-30-32(14-18)15-22-5-7-23(8-6-22)16-33-17-26(21(4)31-33)27(34)29-13-25-19(2)9-24(11-28)10-20(25)3/h5-10,12,14,17H,11,13,15-16,28H2,1-4H3,(H,29,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187100 (US9670157, 114 3-Methyl-1-[4-(4-methyl-pyrazol-1-y...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4c(C)cc(CN)cc4C)c(C)n3)cc2)c1 Show InChI InChI=1S/C27H32N6O/c1-18-12-30-32(14-18)15-22-5-7-23(8-6-22)16-33-17-26(21(4)31-33)27(34)29-13-25-19(2)9-24(11-28)10-20(25)3/h5-10,12,14,17H,11,13,15-16,28H2,1-4H3,(H,29,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187104 (US9670157, 118 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4c(C)cc(CN)cc4C)c(n3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C27H29F3N6O/c1-17-11-33-35(13-17)14-20-4-6-21(7-5-20)15-36-16-24(25(34-36)27(28,29)30)26(37)32-12-23-18(2)8-22(10-31)9-19(23)3/h4-9,11,13,16H,10,12,14-15,31H2,1-3H3,(H,32,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187097 (US9670157, 111 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C26H30N6O/c1-18-11-29-31(14-18)15-21-4-6-22(7-5-21)16-32-17-24(12-30-32)26(33)28-13-25-19(2)8-23(10-27)9-20(25)3/h4-9,11-12,14,17H,10,13,15-16,27H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187104 (US9670157, 118 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4c(C)cc(CN)cc4C)c(n3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C27H29F3N6O/c1-17-11-33-35(13-17)14-20-4-6-21(7-5-20)15-36-16-24(25(34-36)27(28,29)30)26(37)32-12-23-18(2)8-22(10-31)9-19(23)3/h4-9,11,13,16H,10,12,14-15,31H2,1-3H3,(H,32,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187097 (US9670157, 111 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C26H30N6O/c1-18-11-29-31(14-18)15-21-4-6-22(7-5-21)16-32-17-24(12-30-32)26(33)28-13-25-19(2)8-23(10-27)9-20(25)3/h4-9,11-12,14,17H,10,13,15-16,27H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187099 (US9670157, 113 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(nn3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C25H29N7O/c1-17-11-28-31(13-17)14-20-4-6-21(7-5-20)15-32-16-24(29-30-32)25(33)27-12-23-18(2)8-22(10-26)9-19(23)3/h4-9,11,13,16H,10,12,14-15,26H2,1-3H3,(H,27,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187092 (US9670157, 106 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3ccc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C25H28N6O/c1-18-11-28-30(14-18)15-20-3-5-21(6-4-20)16-31-17-24(13-29-31)25(32)27-12-23-8-7-22(10-26)9-19(23)2/h3-9,11,13-14,17H,10,12,15-16,26H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187110 (US9670157, 124 3-Methyl-1-(2-methyl-quinolin-6-ylm...) Show SMILES Cc1nn(Cc2ccc3nc(C)ccc3c2)cc1C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C26H29N5O/c1-16-9-21(12-27)10-17(2)23(16)13-28-26(32)24-15-31(30-19(24)4)14-20-6-8-25-22(11-20)7-5-18(3)29-25/h5-11,15H,12-14,27H2,1-4H3,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187099 (US9670157, 113 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(nn3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C25H29N7O/c1-17-11-28-31(13-17)14-20-4-6-21(7-5-20)15-32-16-24(29-30-32)25(33)27-12-23-18(2)8-22(10-26)9-19(23)3/h4-9,11,13,16H,10,12,14-15,26H2,1-3H3,(H,27,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187098 (US9670157, 112 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cnc(c3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C26H30N6O/c1-18-11-30-32(13-18)15-22-6-4-21(5-7-22)14-31-16-25(29-17-31)26(33)28-12-24-19(2)8-23(10-27)9-20(24)3/h4-9,11,13,16-17H,10,12,14-15,27H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187110 (US9670157, 124 3-Methyl-1-(2-methyl-quinolin-6-ylm...) Show SMILES Cc1nn(Cc2ccc3nc(C)ccc3c2)cc1C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C26H29N5O/c1-16-9-21(12-27)10-17(2)23(16)13-28-26(32)24-15-31(30-19(24)4)14-20-6-8-25-22(11-20)7-5-18(3)29-25/h5-11,15H,12-14,27H2,1-4H3,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187092 (US9670157, 106 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3ccc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C25H28N6O/c1-18-11-28-30(14-18)15-20-3-5-21(6-4-20)16-31-17-24(13-29-31)25(32)27-12-23-8-7-22(10-26)9-19(23)2/h3-9,11,13-14,17H,10,12,15-16,26H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187098 (US9670157, 112 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cnc(c3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C26H30N6O/c1-18-11-30-32(13-18)15-22-6-4-21(5-7-22)14-31-16-25(29-17-31)26(33)28-12-24-19(2)8-23(10-27)9-20(24)3/h4-9,11,13,16-17H,10,12,14-15,27H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187111 (US9670157, 125 5-Methyl-1-(2-methyl-quinolin-6-ylm...) Show SMILES Cc1c(cnn1Cc1ccc2nc(C)ccc2c1)C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C26H29N5O/c1-16-9-21(12-27)10-17(2)23(16)13-28-26(32)24-14-29-31(19(24)4)15-20-6-8-25-22(11-20)7-5-18(3)30-25/h5-11,14H,12-13,15,27H2,1-4H3,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187112 (US9670157, 126 1-(2-Methyl-quinolin-6-ylmethyl)-3-...) Show SMILES Cc1ccc2cc(Cn3cc(C(=O)NCc4c(C)cc(CN)cc4C)c(n3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C26H26F3N5O/c1-15-8-19(11-30)9-16(2)21(15)12-31-25(35)22-14-34(33-24(22)26(27,28)29)13-18-5-7-23-20(10-18)6-4-17(3)32-23/h4-10,14H,11-13,30H2,1-3H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187112 (US9670157, 126 1-(2-Methyl-quinolin-6-ylmethyl)-3-...) Show SMILES Cc1ccc2cc(Cn3cc(C(=O)NCc4c(C)cc(CN)cc4C)c(n3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C26H26F3N5O/c1-15-8-19(11-30)9-16(2)21(15)12-31-25(35)22-14-34(33-24(22)26(27,28)29)13-18-5-7-23-20(10-18)6-4-17(3)32-23/h4-10,14H,11-13,30H2,1-3H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187111 (US9670157, 125 5-Methyl-1-(2-methyl-quinolin-6-ylm...) Show SMILES Cc1c(cnn1Cc1ccc2nc(C)ccc2c1)C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C26H29N5O/c1-16-9-21(12-27)10-17(2)23(16)13-28-26(32)24-14-29-31(19(24)4)15-20-6-8-25-22(11-20)7-5-18(3)30-25/h5-11,14H,12-13,15,27H2,1-4H3,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187093 (US9670157, 107 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cnc(c3)C(=O)NCc3ccc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C25H28N6O/c1-18-11-29-31(13-18)15-21-5-3-20(4-6-21)14-30-16-24(28-17-30)25(32)27-12-23-8-7-22(10-26)9-19(23)2/h3-9,11,13,16-17H,10,12,14-15,26H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187093 (US9670157, 107 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cnc(c3)C(=O)NCc3ccc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C25H28N6O/c1-18-11-29-31(13-18)15-21-5-3-20(4-6-21)14-30-16-24(28-17-30)25(32)27-12-23-8-7-22(10-26)9-19(23)2/h3-9,11,13,16-17H,10,12,14-15,26H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187087 (US9670157, 101 2,5-Dimethyl-1-[4-(4-methyl-pyrazol...) Show SMILES Cc1cnn(Cc2ccc(Cn3c(C)cc(C(=O)NCc4c(C)cc(CN)cc4C)c3C)cc2)c1 Show InChI InChI=1S/C29H35N5O/c1-19-14-32-33(16-19)17-24-6-8-25(9-7-24)18-34-22(4)12-27(23(34)5)29(35)31-15-28-20(2)10-26(13-30)11-21(28)3/h6-12,14,16H,13,15,17-18,30H2,1-5H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187087 (US9670157, 101 2,5-Dimethyl-1-[4-(4-methyl-pyrazol...) Show SMILES Cc1cnn(Cc2ccc(Cn3c(C)cc(C(=O)NCc4c(C)cc(CN)cc4C)c3C)cc2)c1 Show InChI InChI=1S/C29H35N5O/c1-19-14-32-33(16-19)17-24-6-8-25(9-7-24)18-34-22(4)12-27(23(34)5)29(35)31-15-28-20(2)10-26(13-30)11-21(28)3/h6-12,14,16H,13,15,17-18,30H2,1-5H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187095 (US9670157, 109 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(nn3)C(=O)NCc3ccc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C24H27N7O/c1-17-11-27-30(13-17)14-19-3-5-20(6-4-19)15-31-16-23(28-29-31)24(32)26-12-22-8-7-21(10-25)9-18(22)2/h3-9,11,13,16H,10,12,14-15,25H2,1-2H3,(H,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187095 (US9670157, 109 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(nn3)C(=O)NCc3ccc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C24H27N7O/c1-17-11-27-30(13-17)14-19-3-5-20(6-4-19)15-31-16-23(28-29-31)24(32)26-12-22-8-7-21(10-25)9-18(22)2/h3-9,11,13,16H,10,12,14-15,25H2,1-2H3,(H,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186837 (US9670157, 3 2,5-Dimethyl-1-(2-phenyl-thiazol-4-yl...) Show SMILES Cc1cc(C(=O)NCc2c(C)cc(CN)cc2C)c(C)n1Cc1csc(n1)-c1ccccc1 Show InChI InChI=1S/C27H30N4OS/c1-17-10-21(13-28)11-18(2)25(17)14-29-26(32)24-12-19(3)31(20(24)4)15-23-16-33-27(30-23)22-8-6-5-7-9-22/h5-12,16H,13-15,28H2,1-4H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186837 (US9670157, 3 2,5-Dimethyl-1-(2-phenyl-thiazol-4-yl...) Show SMILES Cc1cc(C(=O)NCc2c(C)cc(CN)cc2C)c(C)n1Cc1csc(n1)-c1ccccc1 Show InChI InChI=1S/C27H30N4OS/c1-17-10-21(13-28)11-18(2)25(17)14-29-26(32)24-12-19(3)31(20(24)4)15-23-16-33-27(30-23)22-8-6-5-7-9-22/h5-12,16H,13-15,28H2,1-4H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186920 (US9670157, 86 1-[4-(3,5-Dimethyl-pyrazol-1-ylmethy...) Show SMILES Cc1cc(C)n(Cc2ccc(Cn3cc(cn3)C(=O)NCc3ccc(CN)cc3)cc2)n1 Show InChI InChI=1S/C25H28N6O/c1-18-11-19(2)31(29-18)16-23-9-7-22(8-10-23)15-30-17-24(14-28-30)25(32)27-13-21-5-3-20(12-26)4-6-21/h3-11,14,17H,12-13,15-16,26H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186920 (US9670157, 86 1-[4-(3,5-Dimethyl-pyrazol-1-ylmethy...) Show SMILES Cc1cc(C)n(Cc2ccc(Cn3cc(cn3)C(=O)NCc3ccc(CN)cc3)cc2)n1 Show InChI InChI=1S/C25H28N6O/c1-18-11-19(2)31(29-18)16-23-9-7-22(8-10-23)15-30-17-24(14-28-30)25(32)27-13-21-5-3-20(12-26)4-6-21/h3-11,14,17H,12-13,15-16,26H2,1-2H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM362300 (5-Methyl-1-[4-(4-methyl-pyrazol-1-ylmethyl)-benzyl...) Show SMILES Cc1cnn(Cc2ccc(Cn3ncc(C(=O)NCc4c(C)cc(CN)cc4C)c3C)cc2)c1 Show InChI InChI=1S/C27H32N6O/c1-18-12-30-32(15-18)16-22-5-7-23(8-6-22)17-33-21(4)26(14-31-33)27(34)29-13-25-19(2)9-24(11-28)10-20(25)3/h5-10,12,14-15H,11,13,16-17,28H2,1-4H3,(H,29,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187097 (US9670157, 111 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3c(C)cc(CN)cc3C)cc2)c1 Show InChI InChI=1S/C26H30N6O/c1-18-11-29-31(14-18)15-21-4-6-22(7-5-21)16-32-17-24(12-30-32)26(33)28-13-25-19(2)8-23(10-27)9-20(25)3/h4-9,11-12,14,17H,10,13,15-16,27H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187105 (US9670157, 119 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4ccc(CN)c(F)c4C)c(n3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C26H26F4N6O/c1-16-10-33-35(12-16)13-18-3-5-19(6-4-18)14-36-15-22(24(34-36)26(28,29)30)25(37)32-11-21-8-7-20(9-31)23(27)17(21)2/h3-8,10,12,15H,9,11,13-14,31H2,1-2H3,(H,32,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187105 (US9670157, 119 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4ccc(CN)c(F)c4C)c(n3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C26H26F4N6O/c1-16-10-33-35(12-16)13-18-3-5-19(6-4-18)14-36-15-22(24(34-36)26(28,29)30)25(37)32-11-21-8-7-20(9-31)23(27)17(21)2/h3-8,10,12,15H,9,11,13-14,31H2,1-2H3,(H,32,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187088 (US9670157, 102 1-Ethyl-4-methyl-5-[4-(4-methyl-pyr...) Show SMILES CCn1c(cc(C)c1Cc1ccc(Cn2cc(C)cn2)cc1)C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C30H37N5O/c1-6-35-28(14-24-7-9-25(10-8-24)19-34-18-20(2)16-33-34)23(5)13-29(35)30(36)32-17-27-21(3)11-26(15-31)12-22(27)4/h7-13,16,18H,6,14-15,17,19,31H2,1-5H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186952 (US9670157, 94 2,5-Dimethyl-1-[4-(2-oxo-2H-pyridin-...) Show SMILES Cc1cc(C(=O)NCc2c(C)cc(CN)cc2C)c(C)n1Cc1ccc(Cn2ccccc2=O)cc1 Show InChI InChI=1S/C30H34N4O2/c1-20-13-26(16-31)14-21(2)28(20)17-32-30(36)27-15-22(3)34(23(27)4)19-25-10-8-24(9-11-25)18-33-12-6-5-7-29(33)35/h5-15H,16-19,31H2,1-4H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186919 (US9670157, 85 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-b...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3ccc(CN)cc3)cc2)c1 Show InChI InChI=1S/C24H26N6O/c1-18-11-27-29(14-18)15-21-6-8-22(9-7-21)16-30-17-23(13-28-30)24(31)26-12-20-4-2-19(10-25)3-5-20/h2-9,11,13-14,17H,10,12,15-16,25H2,1H3,(H,26,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186952 (US9670157, 94 2,5-Dimethyl-1-[4-(2-oxo-2H-pyridin-...) Show SMILES Cc1cc(C(=O)NCc2c(C)cc(CN)cc2C)c(C)n1Cc1ccc(Cn2ccccc2=O)cc1 Show InChI InChI=1S/C30H34N4O2/c1-20-13-26(16-31)14-21(2)28(20)17-32-30(36)27-15-22(3)34(23(27)4)19-25-10-8-24(9-11-25)18-33-12-6-5-7-29(33)35/h5-15H,16-19,31H2,1-4H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186919 (US9670157, 85 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-b...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(cn3)C(=O)NCc3ccc(CN)cc3)cc2)c1 Show InChI InChI=1S/C24H26N6O/c1-18-11-27-29(14-18)15-21-6-8-22(9-7-21)16-30-17-23(13-28-30)24(31)26-12-20-4-2-19(10-25)3-5-20/h2-9,11,13-14,17H,10,12,15-16,25H2,1H3,(H,26,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187088 (US9670157, 102 1-Ethyl-4-methyl-5-[4-(4-methyl-pyr...) Show SMILES CCn1c(cc(C)c1Cc1ccc(Cn2cc(C)cn2)cc1)C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C30H37N5O/c1-6-35-28(14-24-7-9-25(10-8-24)19-34-18-20(2)16-33-34)23(5)13-29(35)30(36)32-17-27-21(3)11-26(15-31)12-22(27)4/h7-13,16,18H,6,14-15,17,19,31H2,1-5H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186836 (US9670157, 2 2,5-Dimethyl-1-(2-phenyl-thiazol-4-yl...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)cc2C)c(C)n1Cc1csc(n1)-c1ccccc1 Show InChI InChI=1S/C26H28N4OS/c1-17-11-20(13-27)9-10-22(17)14-28-25(31)24-12-18(2)30(19(24)3)15-23-16-32-26(29-23)21-7-5-4-6-8-21/h4-12,16H,13-15,27H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186836 (US9670157, 2 2,5-Dimethyl-1-(2-phenyl-thiazol-4-yl...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)cc2C)c(C)n1Cc1csc(n1)-c1ccccc1 Show InChI InChI=1S/C26H28N4OS/c1-17-11-20(13-27)9-10-22(17)14-28-25(31)24-12-18(2)30(19(24)3)15-23-16-32-26(29-23)21-7-5-4-6-8-21/h4-12,16H,13-15,27H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM362280 (1-Ethyl-4-methyl-5-[4-(2-oxo-2H-pyridin-1-ylmethyl...) Show SMILES CCn1c(Cc2ccc(Cn3ccccc3=O)cc2)c(C)cc1C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C31H36N4O2/c1-5-35-28(17-24-9-11-25(12-10-24)20-34-13-7-6-8-30(34)36)23(4)16-29(35)31(37)33-19-27-21(2)14-26(18-32)15-22(27)3/h6-16H,5,17-20,32H2,1-4H3,(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186954 (US9670157, 95 1-Ethyl-4-methyl-5-[4-(2-oxo-2H-pyri...) Show SMILES CCc1c(Cc2ccc(Cn3ccccc3=O)cc2)c(C)cc1C(=O)NCc1c(C)cc(CN)cc1C Show InChI InChI=1S/C32H36N3O2/c1-5-27-28(17-24-9-11-25(12-10-24)20-35-13-7-6-8-31(35)36)23(4)16-29(27)32(37)34-19-30-21(2)14-26(18-33)15-22(30)3/h6-16H,5,17-20,33H2,1-4H3,(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187115 (US9670157, 129 1-(2-Pyrrolidin-1-yl-pyridin-4-ylme...) Show SMILES Cc1cc(CN)cc(C)c1CNC(=O)c1cn(Cc2ccnc(c2)N2CCCC2)nc1C(F)(F)F Show InChI InChI=1S/C25H29F3N6O/c1-16-9-19(12-29)10-17(2)20(16)13-31-24(35)21-15-34(32-23(21)25(26,27)28)14-18-5-6-30-22(11-18)33-7-3-4-8-33/h5-6,9-11,15H,3-4,7-8,12-14,29H2,1-2H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM187115 (US9670157, 129 1-(2-Pyrrolidin-1-yl-pyridin-4-ylme...) Show SMILES Cc1cc(CN)cc(C)c1CNC(=O)c1cn(Cc2ccnc(c2)N2CCCC2)nc1C(F)(F)F Show InChI InChI=1S/C25H29F3N6O/c1-16-9-19(12-29)10-17(2)20(16)13-31-24(35)21-15-34(32-23(21)25(26,27)28)14-18-5-6-30-22(11-18)33-7-3-4-8-33/h5-6,9-11,15H,3-4,7-8,12-14,29H2,1-2H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM186956 (US9670157, 97 2,5-Dimethyl-1-[4-(4-methyl-pyrazol-...) Show SMILES Cc1cnn(Cc2ccc(Cn3c(C)cc(C(=O)NCc4ccc(CN)cc4C)c3C)cc2)c1 Show InChI InChI=1S/C28H33N5O/c1-19-14-31-32(16-19)17-23-5-7-24(8-6-23)18-33-21(3)12-27(22(33)4)28(34)30-15-26-10-9-25(13-29)11-20(26)2/h5-12,14,16H,13,15,17-18,29H2,1-4H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair

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