| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dipeptidyl peptidase 2 |
|---|
| Ligand | BDBM50278841 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_501198 (CHEMBL975311) |
|---|
| IC50 | 11100000±n/a nM |
|---|
| Citation |  Benbow, JW; Andrews, KA; Aubrecht, J; Beebe, D; Boyer, D; Doran, S; Homiski, M; Hui, Y; McPherson, K; Parker, JC; Treadway, J; Vanvolkenberg, M; Zembrowski, WJ Piperidinyl-2-phenethylamino inhibitors of DPP-IV for the treatment of type 2 diabetes. Bioorg Med Chem Lett19:2220-3 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dipeptidyl peptidase 2 |
|---|
| Name: | Dipeptidyl peptidase 2 |
|---|
| Synonyms: | DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 54339.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9UHL4 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
QPALRGGPRLSL
|
|
|
|---|
| BDBM50278841 |
|---|
| n/a |
|---|
| Name | BDBM50278841 |
|---|
| Synonyms: | (R)-(4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)piperidin-1-yl)(2,4-difluorophenyl)methanone | CHEMBL497735 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H19F5N2O |
|---|
| Mol. Mass. | 398.3697 |
|---|
| SMILES | N[C@H](Cc1cc(F)c(F)cc1F)C1CCN(CC1)C(=O)c1ccc(F)cc1F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
