| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50216039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563397 (CHEMBL959382) |
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| Ki | 74±n/a nM |
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| Citation |  Medina, RA; Sallander, J; Benhamú, B; Porras, E; Campillo, M; Pardo, L; López-Rodríguez, ML Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity. J Med Chem52:2384-92 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50216039 |
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| n/a |
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| Name | BDBM50216039 |
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| Synonyms: | 1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-indolin-2-one | 1-[4-(4-Phenylpiperazin-1-yl)butyl]-1,3-dihydro-2H-indol-2-one | CHEMBL395933 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N3O |
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| Mol. Mass. | 349.4693 |
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| SMILES | O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 |
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| Structure | 
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