Compile Data Set for Download or QSAR

Found 117 hits with Last Name = 'medina' and Initial = 'ra'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055575 (CHEMBL3321794) Show SMILES O=C1Cc2ccccc2N1CC\C=C\CCN1CCc2ccccc2C1 Show InChI InChI=1S/C23H26N2O/c26-23-17-20-10-5-6-12-22(20)25(23)15-8-2-1-7-14-24-16-13-19-9-3-4-11-21(19)18-24/h1-6,9-12H,7-8,13-18H2/b2-1+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM86428 (SB-258585) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1N1CCN(C)CC1 Show InChI InChI=1S/C18H22IN3O3S/c1-21-9-11-22(12-10-21)17-13-15(5-8-18(17)25-2)20-26(23,24)16-6-3-14(19)4-7-16/h3-8,13,20H,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF as...				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055574 (CHEMBL3321798) Show SMILES [H][C@]12CCCC[C@]1([H])CN(CC\C=C\CCN1C(=O)Cc3ccccc13)CC2 |r| Show InChI InChI=1S/C23H32N2O/c26-23-17-20-10-5-6-12-22(20)25(23)15-8-2-1-7-14-24-16-13-19-9-3-4-11-21(19)18-24/h1-2,5-6,10,12,19,21H,3-4,7-9,11,13-18H2/b2-1+/t19-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304001 (CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(nc12)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N4O/c1-26-12-14-27(15-13-26)20-11-5-10-19-21(20)25-23(24-19)22(28)18-9-4-7-16-6-2-3-8-17(16)18/h2-11H,12-15H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM50304001 (CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(nc12)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N4O/c1-26-12-14-27(15-13-26)20-11-5-10-19-21(20)25-23(24-19)22(28)18-9-4-7-16-6-2-3-8-17(16)18/h2-11H,12-15H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF as...				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267832 (1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C21H24N2O/c24-21-15-18-8-3-4-10-20(18)23(21)13-6-5-12-22-14-11-17-7-1-2-9-19(17)16-22/h1-4,7-10H,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267832 (1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C21H24N2O/c24-21-15-18-8-3-4-10-20(18)23(21)13-6-5-12-22-14-11-17-7-1-2-9-19(17)16-22/h1-4,7-10H,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267739 (1-{(2Z)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) Show SMILES O=C1Cc2ccccc2N1C\C=C/CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H27N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-13H,14-20H2/b6-5-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304003 (1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)m...) Show SMILES O=C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H20N4O/c27-21(17-8-3-6-15-5-1-2-7-16(15)17)22-24-18-9-4-10-19(20(18)25-22)26-13-11-23-12-14-26/h1-10,23H,11-14H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304003 (1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)m...) Show SMILES O=C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H20N4O/c27-21(17-8-3-6-15-5-1-2-7-16(15)17)22-24-18-9-4-10-19(20(18)25-22)26-13-11-23-12-14-26/h1-10,23H,11-14H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267737 (1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dih...) Show SMILES O=C1Cc2ccccc2N1CCCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C27H31N3O/c31-27-21-23-10-3-5-13-25(23)30(27)16-7-1-6-15-28-17-19-29(20-18-28)26-14-8-11-22-9-2-4-12-24(22)26/h2-5,8-14H,1,6-7,15-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304002 (2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimida...) Show SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4/c1-2-8-18-16(5-1)6-3-7-17(18)15-21-24-19-9-4-10-20(22(19)25-21)26-13-11-23-12-14-26/h1-10,23H,11-15H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303997 (2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3ccccc3)nc12 Show InChI InChI=1S/C19H22N4/c1-22-10-12-23(13-11-22)17-9-5-8-16-19(17)21-18(20-16)14-15-6-3-2-4-7-15/h2-9H,10-14H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304002 (2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimida...) Show SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4/c1-2-8-18-16(5-1)6-3-7-17(18)15-21-24-19-9-4-10-20(22(19)25-21)26-13-11-23-12-14-26/h1-10,23H,11-15H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303999 (4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...) Show SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H22N4/c1-2-5-18-14-16(8-9-17(18)4-1)15-21-24-19-6-3-7-20(22(19)25-21)26-12-10-23-11-13-26/h1-9,14,23H,10-13,15H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267738 (1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pent...) Show SMILES O=C1Cc2ccccc2N1CCCCCN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C24H29N5O/c30-23-17-19-7-2-3-9-21(19)29(23)12-5-1-4-11-27-13-15-28(16-14-27)22-10-6-8-20-24(22)26-18-25-20/h2-3,6-10,18H,1,4-5,11-17H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267694 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihy...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H29N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-4,7-13H,5-6,14-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055580 (CHEMBL3321778) Show SMILES O=C1Cc2ccccc2N1CCCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C23H28N2O/c26-23-17-20-10-5-6-12-22(20)25(23)15-8-2-1-7-14-24-16-13-19-9-3-4-11-21(19)18-24/h3-6,9-12H,1-2,7-8,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267783 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3...) Show SMILES O=C1Cc2ccccc2N1CC#CCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H25N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-4,7-13H,14-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12 Show InChI InChI=1S/C23H24N4/c1-26-12-14-27(15-13-26)21-11-5-10-20-23(21)25-22(24-20)16-18-8-4-7-17-6-2-3-9-19(17)18/h2-11H,12-16H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055581 (CHEMBL3321777) Show SMILES O=C1Cc2ccccc2N1CCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C22H26N2O/c25-22-16-19-9-4-5-11-21(19)24(22)14-7-1-6-13-23-15-12-18-8-2-3-10-20(18)17-23/h2-5,8-11H,1,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055578 (CHEMBL3321795) Show SMILES [H][C@]12CCCC[C@]1([H])CN(CCCCN1C(=O)Cc3ccccc13)CC2 |r| Show InChI InChI=1S/C21H30N2O/c24-21-15-18-8-3-4-10-20(18)23(21)13-6-5-12-22-14-11-17-7-1-2-9-19(17)16-22/h3-4,8,10,17,19H,1-2,5-7,9,11-16H2/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303998 (2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...) Show SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C18H20N4/c1-2-5-14(6-3-1)13-17-20-15-7-4-8-16(18(15)21-17)22-11-9-19-10-12-22/h1-8,19H,9-13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50216042 (1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one |...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)Cc3ccccc23)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-20-9-3-2-8-19(20)18-23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304001 (CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(nc12)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N4O/c1-26-12-14-27(15-13-26)20-11-5-10-19-21(20)25-23(24-19)22(28)18-9-4-7-16-6-2-3-8-17(16)18/h2-11H,12-15H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055579 (CHEMBL3321793) Show SMILES O=C1Cc2ccccc2N1CCCCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C24H30N2O/c27-24-18-21-11-6-7-13-23(21)26(24)16-9-3-1-2-8-15-25-17-14-20-10-4-5-12-22(20)19-25/h4-7,10-13H,1-3,8-9,14-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12 Show InChI InChI=1S/C23H24N4/c1-26-12-14-27(15-13-26)21-11-5-10-20-23(21)25-22(24-20)16-18-8-4-7-17-6-2-3-9-19(17)18/h2-11H,12-16H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267740 (1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) Show SMILES O=C1Cc2ccccc2N1C\C=C\CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H27N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-13H,14-20H2/b6-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055577 (CHEMBL3321796) Show SMILES [H][C@]12CCCC[C@]1([H])CN(CCCCCN1C(=O)Cc3ccccc13)CC2 |r| Show InChI InChI=1S/C22H32N2O/c25-22-16-19-9-4-5-11-21(19)24(22)14-7-1-6-13-23-15-12-18-8-2-3-10-20(18)17-23/h4-5,9,11,18,20H,1-3,6-8,10,12-17H2/t18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267694 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihy...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H29N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-4,7-13H,5-6,14-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303999 (4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...) Show SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H22N4/c1-2-5-18-14-16(8-9-17(18)4-1)15-21-24-19-6-3-7-20(22(19)25-21)26-12-10-23-11-13-26/h1-9,14,23H,10-13,15H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303998 (2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...) Show SMILES C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C18H20N4/c1-2-5-14(6-3-1)13-17-20-15-7-4-8-16(18(15)21-17)22-11-9-19-10-12-22/h1-8,19H,9-13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50055576 (CHEMBL3321797) Show SMILES [H][C@]12CCCC[C@]1([H])CN(CCCCCCCN1C(=O)Cc3ccccc13)CC2 |r| Show InChI InChI=1S/C24H36N2O/c27-24-18-21-11-6-7-13-23(21)26(24)16-9-3-1-2-8-15-25-17-14-20-10-4-5-12-22(20)19-25/h6-7,11,13,20,22H,1-5,8-10,12,14-19H2/t20-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267695 (1-[5-(4-Phenylpiperazin-1-yl)pentyl]-1,3-dihydro-2...) Show SMILES O=C1Cc2ccccc2N1CCCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23-19-20-9-5-6-12-22(20)26(23)14-8-2-7-13-24-15-17-25(18-16-24)21-10-3-1-4-11-21/h1,3-6,9-12H,2,7-8,13-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267696 (1-{5-[4-(2-Methoxyphenyl)piperazin-1-yl]pentyl}-1,...) Show SMILES COc1ccccc1N1CCN(CCCCCN2C(=O)Cc3ccccc23)CC1 Show InChI InChI=1S/C24H31N3O2/c1-29-23-12-6-5-11-22(23)26-17-15-25(16-18-26)13-7-2-8-14-27-21-10-4-3-9-20(21)19-24(27)28/h3-6,9-12H,2,7-8,13-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303997 (2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...) Show SMILES CN1CCN(CC1)c1cccc2[nH]c(Cc3ccccc3)nc12 Show InChI InChI=1S/C19H22N4/c1-22-10-12-23(13-11-22)17-9-5-8-16-19(17)21-18(20-16)14-15-6-3-2-4-7-15/h2-9H,10-14H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267738 (1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pent...) Show SMILES O=C1Cc2ccccc2N1CCCCCN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C24H29N5O/c30-23-17-19-7-2-3-9-21(19)29(23)12-5-1-4-11-27-13-15-28(16-14-27)22-10-6-8-20-24(22)26-18-25-20/h2-3,6-10,18H,1,4-5,11-17H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267740 (1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) Show SMILES O=C1Cc2ccccc2N1C\C=C\CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H27N3O/c30-26-20-22-9-2-4-12-24(22)29(26)15-6-5-14-27-16-18-28(19-17-27)25-13-7-10-21-8-1-3-11-23(21)25/h1-13H,14-20H2/b6-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267737 (1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dih...) Show SMILES O=C1Cc2ccccc2N1CCCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C27H31N3O/c31-27-21-23-10-3-5-13-25(23)30(27)16-7-1-6-15-28-17-19-29(20-18-28)26-14-8-11-22-9-2-4-12-24(22)26/h2-5,8-14H,1,6-7,15-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c26-22-18-19-8-4-5-11-21(19)25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50240359 (1-(5-(4-phenylpiperazin-1-yl)pentyl)benzo[cd]indol...) Show SMILES O=C1N(CCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23 Show InChI InChI=1S/C26H29N3O/c30-26-23-13-7-9-21-10-8-14-24(25(21)23)29(26)16-6-2-5-15-27-17-19-28(20-18-27)22-11-3-1-4-12-22/h1,3-4,7-14H,2,5-6,15-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267833 (1-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)propyl]-1,3-...) Show SMILES O=C1Cc2ccccc2N1CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C20H22N2O/c23-20-14-17-7-3-4-9-19(17)22(20)12-5-11-21-13-10-16-6-1-2-8-18(16)15-21/h1-4,6-9H,5,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c26-22-18-19-8-4-5-11-21(19)25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267786 (1-[4-(4-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C23H28N2O/c26-23-18-21-10-4-5-11-22(21)25(23)15-7-6-14-24-16-12-20(13-17-24)19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267785 (1-(4-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)...) Show SMILES O=C1Cc2ccccc2N1Cc1ccc(CN2CCN(CC2)c2cccc3ccccc23)cc1 Show InChI InChI=1S/C30H29N3O/c34-30-20-26-7-2-4-10-28(26)33(30)22-24-14-12-23(13-15-24)21-31-16-18-32(19-17-31)29-11-5-8-25-6-1-3-9-27(25)29/h1-15H,16-22H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267831 (1-[4-(3-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCCC(C1)c1ccccc1 Show InChI InChI=1S/C23H28N2O/c26-23-17-20-11-4-5-13-22(20)25(23)16-7-6-14-24-15-8-12-21(18-24)19-9-2-1-3-10-19/h1-5,9-11,13,21H,6-8,12,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	193	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267655 (2-[5-(4-Phenylpiperazin-1-yl)pentyl]isoindolin-1-o...) Show SMILES O=C1N(CCCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C23H29N3O/c27-23-22-12-6-5-9-20(22)19-26(23)14-8-2-7-13-24-15-17-25(18-16-24)21-10-3-1-4-11-21/h1,3-6,9-12H,2,7-8,13-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267832 (1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C21H24N2O/c24-21-15-18-8-3-4-10-20(18)23(21)13-6-5-12-22-14-11-17-7-1-2-9-19(17)16-22/h1-4,7-10H,5-6,11-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	219	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells				J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267832 (1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C21H24N2O/c24-21-15-18-8-3-4-10-20(18)23(21)13-6-5-12-22-14-11-17-7-1-2-9-19(17)16-22/h1-4,7-10H,5-6,11-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	219	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometry				J Med Chem 57: 6879-84 (2014) Article DOI: 10.1021/jm500880c BindingDB Entry DOI: 10.7270/Q2J104TB
					More data for this Ligand-Target Pair

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