Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50030815 (CHEMBL404594) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50236697 (5-L-isoleucineangiotensin II | 5-isoleucine-angiot...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3... | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50009338 ((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-((S)-5-(d...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (MOUSE) | BDBM86428 (SB-258585) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF as... | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304001 (CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (MOUSE) | BDBM50304001 (CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at mouse wild type 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF as... | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267832 (1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267739 (1-{(2Z)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50145197 (CHEMBL3394207) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304003 (1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304003 (1-Naphthyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267737 (1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dih...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50303997 (2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304002 (2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimida...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304002 (2-(1-Naphthylmethyl)-4-piperazin-1-yl-1H-benzimida...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50303999 (4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50030814 (CHEMBL2086892) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267738 (1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 18.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267694 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267783 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50303998 (2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Antagonist activity at human 5HT6 receptor expressed in COS7 cells assessed as inhibition of seratonin-induced cAMP accumulation by HTRF assay | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50216042 (1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304001 (CHEMBL584690 | [4-(4-Methylpiperazin-1-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50304000 (4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267740 (1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50049182 ((S)-5-Benzyloxy-2-diphenylacetyl-6-methoxy-1,2,3,4...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin) | Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267694 (1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50303999 (4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50303998 (2-Benzyl-4-piperazin-1-yl-1H-benzimidazole | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267695 (1-[5-(4-Phenylpiperazin-1-yl)pentyl]-1,3-dihydro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267696 (1-{5-[4-(2-Methoxyphenyl)piperazin-1-yl]pentyl}-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50303997 (2-Benzyl-4-(4-methylpiperazin-1-yl)-1H-benzimidazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 66.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting | J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267738 (1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pent...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267737 (1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dih...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267740 (1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50240359 (1-(5-(4-phenylpiperazin-1-yl)pentyl)benzo[cd]indol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267833 (1-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)propyl]-1,3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267786 (1-[4-(4-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267785 (1-(4-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 181 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267831 (1-[4-(3-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 193 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267655 (2-[5-(4-Phenylpiperazin-1-yl)pentyl]isoindolin-1-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 203 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50267832 (1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267739 (1-{(2Z)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50267834 (1-[2-(3,4-Dihydroisoquinolin-2(1H)-yl)ethyl]-1,3-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense de Madrid Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells | J Med Chem 52: 2384-92 (2009) Article DOI: 10.1021/jm8014553 BindingDB Entry DOI: 10.7270/Q2B8580P | |||||||||||
More data for this Ligand-Target Pair |
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