| Reaction Details |
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 | Report a problem with these data |
| Target | Motilin receptor |
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| Ligand | BDBM50268430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_523907 (CHEMBL1001500) |
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| IC50 | 1.1±n/a nM |
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| Citation |  Taka, N; Matsuoka, H; Sato, T; Yoshino, H; Imaoka, I; Sato, H; Kotake, K; Kumagai, Y; Kamei, K; Ozaki, K; Higashida, A; Kuroki, T Discovery of novel motilin antagonists: Conversion of tetrapeptide leads to orally available peptidomimetics. Bioorg Med Chem Lett19:3426-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Motilin receptor |
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| Name: | Motilin receptor |
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| Synonyms: | n/a |
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| Type: | n/a |
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| Mol. Mass.: | 43771.25 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MGSPWNGSDGPEDAREPPWAALPPCDERRCSPFPLGTLVPVTAVCLGLFAVGVSGNVVTV
LLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGQLLCRLSLYVGEG
CTYASLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAALWAVALLSAGPFFFLVGVE
QDPAVFAAPDRNGTVPLDPSSPAPASPPSGPGAEAAALFSRECRPSRAQLGLLRVMLWVT
TAYFFLPFLCLSILYGLIARQLWRGRGPLRGPAATGRERGHRQTVRVLLVVVLAFIVCWL
PFHVGRIIYINTQDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAARRLLRE
SRAGPSGVCGSRGPEQDVAGDTGGDTAGCTETSANTKTAA
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| BDBM50268430 |
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| n/a |
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| Name | BDBM50268430 |
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| Synonyms: | (S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl)-1-oxopropan-2-yl)-2-((S)-2-amino-N-methyl-3-phenylpropanamido)-3-methylbutanamide | CHEMBL496391 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H40N4O4 |
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| Mol. Mass. | 496.6416 |
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| SMILES | CC(C)[C@H](N(C)C(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O |r| |
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| Structure | 
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