| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division cycle 7-related protein kinase |
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| Ligand | BDBM50279183 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_546026 (CHEMBL1034201) |
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| IC50 | 162±n/a nM |
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| Citation |  Ermoli, A; Bargiotti, A; Brasca, MG; Ciavolella, A; Colombo, N; Fachin, G; Isacchi, A; Menichincheri, M; Molinari, A; Montagnoli, A; Pillan, A; Rainoldi, S; Sirtori, FR; Sola, F; Thieffine, S; Tibolla, M; Valsasina, B; Volpi, D; Santocanale, C; Vanotti, E Cell division cycle 7 kinase inhibitors: 1H-pyrrolo[2,3-b]pyridines, synthesis and structure-activity relationships. J Med Chem52:4380-90 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division cycle 7-related protein kinase |
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| Name: | Cell division cycle 7-related protein kinase |
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| Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 |
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| Type: | Protein |
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| Mol. Mass.: | 63908.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00311 |
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| Residue: | 574 |
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| Sequence: | MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKI
EDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGV
KYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKP
SNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSG
PVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH
ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVC
SICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDD
LTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQ
GHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPD
EAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL
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| BDBM50279183 |
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| n/a |
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| Name | BDBM50279183 |
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| Synonyms: | (Z)-2-[(4-Methylbenzyl)amino]-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-3,5-dihydro-4H-imidazol-4-one | CHEMBL498275 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N5O |
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| Mol. Mass. | 331.3712 |
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| SMILES | Cc1ccc(CNC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)cc1 |w:10.10,t:7| |
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| Structure | 
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