| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsin-like elastase family member 2A |
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| Ligand | BDBM50199883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_194721 (CHEMBL807702) |
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| IC50 | 700±n/a nM |
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| Citation |  Adonias, M; Anayaba, J; Cámara, J; Canet, E; Gateau-Olesker, A; Gero, SD; Grande, M; Hernando, JI Enantioselective synthesis and antielastase activity of 1,3,4-trisubstituted and 3,4-disubstituted β-lactam antibiotics Bioorg Med Chem Lett3:2547-2552 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsin-like elastase family member 2A |
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| Name: | Chymotrypsin-like elastase family member 2A |
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| Synonyms: | CEL2A_RAT | Cela2a | Ela2 | Ela2a | Elastase 2A | Elastase-2 | Elastase-2A |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28894.94 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_194721 |
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| Residue: | 271 |
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| Sequence: | MIRTLLLSALVAGALSCGYPTYEVQHDVSRVVGGQEASPNSWPWQVSLQYLSSGKWHHTC
GGSLVANNWVLTAAHCISNSRTYRVLLGRHSLSTSESGSLAVQVSKLVVHEKWNAQKLSN
GNDIALVKLASPVALTSKIQTACLPPAGTILPNNYPCYVTGWGRLQTNGATPDVLQQGRL
LVVDYATCSSASWWGSSVKTNMVCAGGDGVTSSCNGDSGGPLNCQASNGQWQVHGIVSFG
STLGCNYPRKPSVFTRVSNYIDWINSVIAKN
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| BDBM50199883 |
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| n/a |
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| Name | BDBM50199883 |
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| Synonyms: | 3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-isochromen-1-one | 3,4-dichloro-1H-isochromen-1-one | 3,4-dichloroisocoumarin | CHEMBL24983 | cid_1609 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H4Cl2O2 |
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| Mol. Mass. | 215.033 |
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| SMILES | Clc1oc(=O)c2ccccc2c1Cl |
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| Structure | 
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