Found 30 hits with Last Name = 'anayaba' and Initial = 'j' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50199883
(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)Show InChI InChI=1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
| Article
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281090
((3S,4R)-1-Acetyl-3-methoxy-4-phenyl-azetidin-2-one...)Show InChI InChI=1S/C12H13NO3/c1-8(14)13-10(11(16-2)12(13)15)9-6-4-3-5-7-9/h3-7,10-11H,1-2H3/t10-,11+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281089
((3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-pheny...)Show SMILES CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C15H17NO3/c1-10(9-12-7-5-4-6-8-12)13-14(19-3)15(18)16(13)11(2)17/h4-9,13-14H,1-3H3/b10-9+/t13-,14+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281090
((3S,4R)-1-Acetyl-3-methoxy-4-phenyl-azetidin-2-one...)Show InChI InChI=1S/C12H13NO3/c1-8(14)13-10(11(16-2)12(13)15)9-6-4-3-5-7-9/h3-7,10-11H,1-2H3/t10-,11+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50199883
(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)Show InChI InChI=1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
| Article
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50199883
(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)Show InChI InChI=1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
| Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281089
((3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-pheny...)Show SMILES CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C15H17NO3/c1-10(9-12-7-5-4-6-8-12)13-14(19-3)15(18)16(13)11(2)17/h4-9,13-14H,1-3H3/b10-9+/t13-,14+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281089
((3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-pheny...)Show SMILES CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C15H17NO3/c1-10(9-12-7-5-4-6-8-12)13-14(19-3)15(18)16(13)11(2)17/h4-9,13-14H,1-3H3/b10-9+/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281090
((3S,4R)-1-Acetyl-3-methoxy-4-phenyl-azetidin-2-one...)Show InChI InChI=1S/C12H13NO3/c1-8(14)13-10(11(16-2)12(13)15)9-6-4-3-5-7-9/h3-7,10-11H,1-2H3/t10-,11+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281092
((3S,4S)-1,4-Diacetyl-3-methoxy-azetidin-2-one | CH...)Show InChI InChI=1S/C8H11NO4/c1-4(10)6-7(13-3)8(12)9(6)5(2)11/h6-7H,1-3H3/t6-,7+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281093
((3S,4S)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2...)Show SMILES CCCC[C@H]1[C@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C31H45NO5S2/c1-7-8-15-22-24(20(2)18-21-13-10-9-11-14-21)32(28(22)33)25(29-38-16-12-17-39-29)27-26(36-31(5,6)37-27)23-19-34-30(3,4)35-23/h9-11,13-14,18,22-27,29H,7-8,12,15-17,19H2,1-6H3/b20-18+/t22-,23?,24+,25+,26?,27?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281094
((3R,4R)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2...)Show SMILES CCCC[C@@H]1[C@@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C31H45NO5S2/c1-7-8-15-22-24(20(2)18-21-13-10-9-11-14-21)32(28(22)33)25(29-38-16-12-17-39-29)27-26(36-31(5,6)37-27)23-19-34-30(3,4)35-23/h9-11,13-14,18,22-27,29H,7-8,12,15-17,19H2,1-6H3/b20-18+/t22-,23?,24+,25-,26?,27?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281088
((3S,4R)-1-[(R)-[1,3]Dithian-2-yl-(2,2,2',2'-tetram...)Show SMILES CO[C@H]1[C@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C28H39NO6S2/c1-17(15-18-11-8-7-9-12-18)20-24(31-6)25(30)29(20)21(26-36-13-10-14-37-26)23-22(34-28(4,5)35-23)19-16-32-27(2,3)33-19/h7-9,11-12,15,19-24,26H,10,13-14,16H2,1-6H3/b17-15+/t19?,20-,21-,22?,23?,24+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281092
((3S,4S)-1,4-Diacetyl-3-methoxy-azetidin-2-one | CH...)Show InChI InChI=1S/C8H11NO4/c1-4(10)6-7(13-3)8(12)9(6)5(2)11/h6-7H,1-3H3/t6-,7+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281086
((3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one | CHEM...)Show InChI InChI=1S/C11H17NO3/c1-4-5-6-9-10(7(2)13)12(8(3)14)11(9)15/h9-10H,4-6H2,1-3H3/t9-,10+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281091
((3S,4S)-1-Acetyl-3-butyl-4-((E)-1-methyl-2-phenyl-...)Show SMILES CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C18H23NO2/c1-4-5-11-16-17(19(14(3)20)18(16)21)13(2)12-15-9-7-6-8-10-15/h6-10,12,16-17H,4-5,11H2,1-3H3/b13-12+/t16-,17+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281086
((3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one | CHEM...)Show InChI InChI=1S/C11H17NO3/c1-4-5-6-9-10(7(2)13)12(8(3)14)11(9)15/h9-10H,4-6H2,1-3H3/t9-,10+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281091
((3S,4S)-1-Acetyl-3-butyl-4-((E)-1-methyl-2-phenyl-...)Show SMILES CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C18H23NO2/c1-4-5-11-16-17(19(14(3)20)18(16)21)13(2)12-15-9-7-6-8-10-15/h6-10,12,16-17H,4-5,11H2,1-3H3/b13-12+/t16-,17+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281087
((3R,4S)-1-[(R)-[1,3]Dithian-2-yl-(2,2,2',2'-tetram...)Show SMILES CO[C@@H]1[C@H](\C=C\c2ccccc2)N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O Show InChI InChI=1S/C27H37NO6S2/c1-26(2)31-16-19(32-26)22-23(34-27(3,4)33-22)20(25-35-14-9-15-36-25)28-18(21(30-5)24(28)29)13-12-17-10-7-6-8-11-17/h6-8,10-13,18-23,25H,9,14-16H2,1-5H3/b13-12+/t18-,19?,20+,21+,22?,23?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 7.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50281092
((3S,4S)-1,4-Diacetyl-3-methoxy-azetidin-2-one | CH...)Show InChI InChI=1S/C8H11NO4/c1-4(10)6-7(13-3)8(12)9(6)5(2)11/h6-7H,1-3H3/t6-,7+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281091
((3S,4S)-1-Acetyl-3-butyl-4-((E)-1-methyl-2-phenyl-...)Show SMILES CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C18H23NO2/c1-4-5-11-16-17(19(14(3)20)18(16)21)13(2)12-15-9-7-6-8-10-15/h6-10,12,16-17H,4-5,11H2,1-3H3/b13-12+/t16-,17+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | >1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281086
((3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one | CHEM...)Show InChI InChI=1S/C11H17NO3/c1-4-5-6-9-10(7(2)13)12(8(3)14)11(9)15/h9-10H,4-6H2,1-3H3/t9-,10+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | >1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE) |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281094
((3R,4R)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2...)Show SMILES CCCC[C@@H]1[C@@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C31H45NO5S2/c1-7-8-15-22-24(20(2)18-21-13-10-9-11-14-21)32(28(22)33)25(29-38-16-12-17-39-29)27-26(36-31(5,6)37-27)23-19-34-30(3,4)35-23/h9-11,13-14,18,22-27,29H,7-8,12,15-17,19H2,1-6H3/b20-18+/t22-,23?,24+,25-,26?,27?/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281093
((3S,4S)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2...)Show SMILES CCCC[C@H]1[C@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C31H45NO5S2/c1-7-8-15-22-24(20(2)18-21-13-10-9-11-14-21)32(28(22)33)25(29-38-16-12-17-39-29)27-26(36-31(5,6)37-27)23-19-34-30(3,4)35-23/h9-11,13-14,18,22-27,29H,7-8,12,15-17,19H2,1-6H3/b20-18+/t22-,23?,24+,25+,26?,27?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281094
((3R,4R)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2...)Show SMILES CCCC[C@@H]1[C@@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C31H45NO5S2/c1-7-8-15-22-24(20(2)18-21-13-10-9-11-14-21)32(28(22)33)25(29-38-16-12-17-39-29)27-26(36-31(5,6)37-27)23-19-34-30(3,4)35-23/h9-11,13-14,18,22-27,29H,7-8,12,15-17,19H2,1-6H3/b20-18+/t22-,23?,24+,25-,26?,27?/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281088
((3S,4R)-1-[(R)-[1,3]Dithian-2-yl-(2,2,2',2'-tetram...)Show SMILES CO[C@H]1[C@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C28H39NO6S2/c1-17(15-18-11-8-7-9-12-18)20-24(31-6)25(30)29(20)21(26-36-13-10-14-37-26)23-22(34-28(4,5)35-23)19-16-32-27(2,3)33-19/h7-9,11-12,15,19-24,26H,10,13-14,16H2,1-6H3/b17-15+/t19?,20-,21-,22?,23?,24+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281093
((3S,4S)-3-Butyl-1-[(R)-[1,3]dithian-2-yl-(2,2,2',2...)Show SMILES CCCC[C@H]1[C@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C31H45NO5S2/c1-7-8-15-22-24(20(2)18-21-13-10-9-11-14-21)32(28(22)33)25(29-38-16-12-17-39-29)27-26(36-31(5,6)37-27)23-19-34-30(3,4)35-23/h9-11,13-14,18,22-27,29H,7-8,12,15-17,19H2,1-6H3/b20-18+/t22-,23?,24+,25+,26?,27?/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281088
((3S,4R)-1-[(R)-[1,3]Dithian-2-yl-(2,2,2',2'-tetram...)Show SMILES CO[C@H]1[C@H](N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C28H39NO6S2/c1-17(15-18-11-8-7-9-12-18)20-24(31-6)25(30)29(20)21(26-36-13-10-14-37-26)23-22(34-28(4,5)35-23)19-16-32-27(2,3)33-19/h7-9,11-12,15,19-24,26H,10,13-14,16H2,1-6H3/b17-15+/t19?,20-,21-,22?,23?,24+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Rattus norvegicus) | BDBM50281087
((3R,4S)-1-[(R)-[1,3]Dithian-2-yl-(2,2,2',2'-tetram...)Show SMILES CO[C@@H]1[C@H](\C=C\c2ccccc2)N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O Show InChI InChI=1S/C27H37NO6S2/c1-26(2)31-16-19(32-26)22-23(34-27(3,4)33-22)20(25-35-14-9-15-36-25)28-18(21(30-5)24(28)29)13-12-17-10-7-6-8-11-17/h6-8,10-13,18-23,25H,9,14-16H2,1-5H3/b13-12+/t18-,19?,20+,21+,22?,23?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 2A
(Sus scrofa) | BDBM50281087
((3R,4S)-1-[(R)-[1,3]Dithian-2-yl-(2,2,2',2'-tetram...)Show SMILES CO[C@@H]1[C@H](\C=C\c2ccccc2)N([C@H](C2OC(C)(C)OC2C2COC(C)(C)O2)C2SCCCS2)C1=O Show InChI InChI=1S/C27H37NO6S2/c1-26(2)31-16-19(32-26)22-23(34-27(3,4)33-22)20(25-35-14-9-15-36-25)28-18(21(30-5)24(28)29)13-12-17-10-7-6-8-11-17/h6-8,10-13,18-23,25H,9,14-16H2,1-5H3/b13-12+/t18-,19?,20+,21+,22?,23?/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE); Not Active |
Bioorg Med Chem Lett 3: 2547-2552 (1993)
Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW |
More data for this Ligand-Target Pair | |