Ki Summary

Reaction Details

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Target

Neurotensin receptor type 1

Ligand

BDBM50281785

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_144293 (CHEMBL754794)

0.100000±n/a nM

Citation

Henry, JA; Horwell, DC; Meecham, KG; Rees, DC A structure-affinity study of the amino acid side-chains in neurotensin : N and C terminal deletions and Ala-scan Bioorg Med Chem Lett3:949-952 (1993) Article

More Info.:

Get all data from this article, Assay Method

Neurotensin receptor type 1

Name:

Neurotensin receptor type 1

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

47237.04

Organism:

MOUSE

Description:

Neurotensin 1 NTSR1 MOUSE::A2ACT4

Residue:

424

Sequence:

MHLNSSVQQGAPSEPGAQPFPHPQFGLETMLLALSLSNGSGNSSESILEPNSNLDVNTDI
YSKVLVTAVYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGLQNRSADGQHPGGLVCTPTVDTATVKVVIQVN
TFMSFLFPMLIISILNTVIANKLTVMVHQAAEQGRGVCTVGTHNSLEHSTFNMSIEPGRV
QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYV
SSAINPILYNLVSANFRQVFLSTLACLCPGWRRRRKKRPTFSRKPNSMSSNHAFSTSATR
ETLY

BDBM50281785

n/a

Name

BDBM50281785

Synonyms:

(S)-2-{2-[(S)-2-{[(S)-1-((S)-2-{(S)-2-[((S)-1-Acetyl-pyrrolidine-2-carbonyl)-amino]-5-guanidino-pentanoylamino}-5-guanidino-pentanoyl)-pyrrolidine-2-carbonyl]-amino}-3-(4-hydroxy-phenyl)-1-oxo-propylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid | CHEMBL174771

Type

Small organic molecule

Emp. Form.

C45H73N13O10

Mol. Mass.

956.1422

SMILES

CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

Structure