Found 18 hits with Last Name = 'meecham' and Initial = 'kg' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neurotensin receptor type 1
(MOUSE) | BDBM50281791
(Ac-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C55H91N17O13/c1-6-31(4)44(50(81)69-40(53(84)85)27-30(2)3)70-47(78)38(28-33-18-20-34(74)21-19-33)68-49(80)42-17-12-26-72(42)52(83)37(15-10-24-63-55(60)61)66-45(76)35(14-9-23-62-54(58)59)65-48(79)41-16-11-25-71(41)51(82)36(13-7-8-22-56)67-46(77)39(29-43(57)75)64-32(5)73/h18-21,30-31,35-42,44,74H,6-17,22-29,56H2,1-5H3,(H2,57,75)(H,64,73)(H,65,79)(H,66,76)(H,67,77)(H,68,80)(H,69,81)(H,70,78)(H,84,85)(H4,58,59,62)(H4,60,61,63)/t31-,35+,36+,37+,38+,39+,40+,41+,42+,44+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50240845
((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...)Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25+,26+,27+,28+,29+,30+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281781
(Ac-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL2645...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C51H85N15O11/c1-6-30(4)41(46(73)63-38(49(76)77)27-29(2)3)64-43(70)37(28-32-18-20-33(68)21-19-32)62-45(72)40-17-12-26-66(40)48(75)36(15-10-24-58-51(55)56)61-42(69)34(14-9-23-57-50(53)54)60-44(71)39-16-11-25-65(39)47(74)35(59-31(5)67)13-7-8-22-52/h18-21,29-30,34-41,68H,6-17,22-28,52H2,1-5H3,(H,59,67)(H,60,71)(H,61,69)(H,62,72)(H,63,73)(H,64,70)(H,76,77)(H4,53,54,57)(H4,55,56,58)/t30-,34+,35+,36+,37+,38+,39+,40+,41+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281785
((S)-2-{2-[(S)-2-{[(S)-1-((S)-2-{(S)-2-[((S)-1-Acet...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C45H73N13O10/c1-6-26(4)36(41(65)55-33(43(67)68)23-25(2)3)56-38(62)32(24-28-15-17-29(60)18-16-28)54-40(64)35-14-10-22-58(35)42(66)31(12-8-20-51-45(48)49)53-37(61)30(11-7-19-50-44(46)47)52-39(63)34-13-9-21-57(34)27(5)59/h15-18,25-26,30-36,60H,6-14,19-24H2,1-5H3,(H,52,63)(H,53,61)(H,54,64)(H,55,65)(H,56,62)(H,67,68)(H4,46,47,50)(H4,48,49,51)/t26-,30+,31+,32+,33+,34+,35+,36+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281793
(Ac-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C75H118N20O19/c1-8-42(6)61(70(110)92-56(73(113)114)36-41(4)5)93-67(107)54(38-45-22-26-47(98)27-23-45)91-69(109)58-19-14-34-95(58)72(112)51(17-12-32-83-75(80)81)87-62(102)48(16-11-31-82-74(78)79)86-68(108)57-18-13-33-94(57)71(111)50(15-9-10-30-76)88-66(106)55(39-59(77)99)90-63(103)49(28-29-60(100)101)85-65(105)53(37-44-20-24-46(97)25-21-44)89-64(104)52(35-40(2)3)84-43(7)96/h20-27,40-42,48-58,61,97-98H,8-19,28-39,76H2,1-7H3,(H2,77,99)(H,84,96)(H,85,105)(H,86,108)(H,87,102)(H,88,106)(H,89,104)(H,90,103)(H,91,109)(H,92,110)(H,93,107)(H,100,101)(H,113,114)(H4,78,79,82)(H4,80,81,83)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,61+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281795
(Ac-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CH...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C60H98N18O16/c1-6-33(4)48(55(90)75-43(58(93)94)29-32(2)3)76-52(87)41(30-35-18-20-36(80)21-19-35)74-54(89)45-17-12-28-78(45)57(92)40(15-10-26-68-60(65)66)71-49(84)37(14-9-25-67-59(63)64)70-53(88)44-16-11-27-77(44)56(91)39(13-7-8-24-61)72-51(86)42(31-46(62)81)73-50(85)38(69-34(5)79)22-23-47(82)83/h18-21,32-33,37-45,48,80H,6-17,22-31,61H2,1-5H3,(H2,62,81)(H,69,79)(H,70,88)(H,71,84)(H,72,86)(H,73,85)(H,74,89)(H,75,90)(H,76,87)(H,82,83)(H,93,94)(H4,63,64,67)(H4,65,66,68)/t33-,37+,38+,39+,40+,41+,42+,43+,44+,45+,48+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50240844
((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-aceta...)Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C40H66N12O9/c1-6-23(4)32(36(58)50-30(38(60)61)20-22(2)3)51-34(56)29(21-25-13-15-26(54)16-14-25)49-35(57)31-12-9-19-52(31)37(59)28(11-8-18-46-40(43)44)48-33(55)27(47-24(5)53)10-7-17-45-39(41)42/h13-16,22-23,27-32,54H,6-12,17-21H2,1-5H3,(H,47,53)(H,48,55)(H,49,57)(H,50,58)(H,51,56)(H,60,61)(H4,41,42,45)(H4,43,44,46)/t23-,27+,28+,29+,30+,31+,32+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50130880
(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6](=O)-[#7]-1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C78H121N21O20/c1-7-43(6)63(73(115)96-57(76(118)119)37-42(4)5)97-70(112)55(39-45-21-25-47(101)26-22-45)95-72(114)59-18-13-35-99(59)75(117)52(16-11-33-86-78(83)84)90-64(106)48(15-10-32-85-77(81)82)89-71(113)58-17-12-34-98(58)74(116)51(14-8-9-31-79)91-69(111)56(40-60(80)102)94-66(108)50(28-30-62(104)105)88-68(110)54(38-44-19-23-46(100)24-20-44)93-67(109)53(36-41(2)3)92-65(107)49-27-29-61(103)87-49/h19-26,41-43,48-59,63,100-101H,7-18,27-40,79H2,1-6H3,(H2,80,102)(H,87,103)(H,88,110)(H,89,113)(H,90,106)(H,91,111)(H,92,107)(H,93,109)(H,94,108)(H,95,114)(H,96,115)(H,97,112)(H,104,105)(H,118,119)(H4,81,82,85)(H4,83,84,86)/t43-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,63-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration producing half maximal inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptor in neonatal mouse whole brain (minus cereb... |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281784
(Ac-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH ...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C69H107N19O18/c1-6-38(4)56(64(102)85-51(67(105)106)33-37(2)3)86-61(99)49(35-41-20-24-43(91)25-21-41)84-63(101)53-17-12-32-88(53)66(104)47(15-10-30-77-69(74)75)81-57(95)44(14-9-29-76-68(72)73)80-62(100)52-16-11-31-87(52)65(103)46(13-7-8-28-70)82-60(98)50(36-54(71)92)83-58(96)45(26-27-55(93)94)79-59(97)48(78-39(5)89)34-40-18-22-42(90)23-19-40/h18-25,37-38,44-53,56,90-91H,6-17,26-36,70H2,1-5H3,(H2,71,92)(H,78,89)(H,79,97)(H,80,100)(H,81,95)(H,82,98)(H,83,96)(H,84,101)(H,85,102)(H,86,99)(H,93,94)(H,105,106)(H4,72,73,76)(H4,74,75,77)/t38-,44+,45+,46+,47+,48+,49+,50+,51+,52+,53+,56+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281787
((1S,4R)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-propio...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)N)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C35H57N9O8/c1-6-20(4)28(32(49)42-26(34(51)52)17-19(2)3)43-30(47)25(18-22-11-13-23(45)14-12-22)41-31(48)27-10-8-16-44(27)33(50)24(40-29(46)21(5)36)9-7-15-39-35(37)38/h11-14,19-21,24-28,45H,6-10,15-18,36H2,1-5H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)(H,51,52)(H4,37,38,39)/t20-,21+,24+,25+,26+,27+,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281794
((S)-2-{(2S,3R)-2-[(S)-2-{2-[2-((S)-2-(S)-Amino-5-g...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C36H62N12O8/c1-6-20(4)28(33(54)47-27(34(55)56)17-19(2)3)48-32(53)26(18-22-11-13-23(49)14-12-22)46-29(50)21(5)44-31(52)25(10-8-16-43-36(40)41)45-30(51)24(37)9-7-15-42-35(38)39/h11-14,19-21,24-28,49H,6-10,15-18,37H2,1-5H3,(H,44,52)(H,45,51)(H,46,50)(H,47,54)(H,48,53)(H,55,56)(H4,38,39,42)(H4,40,41,43)/t20-,21+,24+,25+,26+,27+,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 0.920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281782
((1S,4R)-2-{2-[2-[((S)-{(S)-1-[2-((S)-2-Amino-5-gua...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C35H57N9O8/c1-6-20(4)28(32(49)42-26(34(51)52)17-19(2)3)43-30(47)25(18-22-11-13-23(45)14-12-22)41-31(48)27-10-8-16-44(27)33(50)21(5)40-29(46)24(36)9-7-15-39-35(37)38/h11-14,19-21,24-28,45H,6-10,15-18,36H2,1-5H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)(H,51,52)(H4,37,38,39)/t20-,21+,24+,25+,26+,27+,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281786
(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(O)=O Show InChI InChI=1S/C35H58N12O8/c1-19(2)17-26(33(54)55)46-28(49)20(3)43-30(51)25(18-21-10-12-22(48)13-11-21)45-31(52)27-9-6-16-47(27)32(53)24(8-5-15-42-35(39)40)44-29(50)23(36)7-4-14-41-34(37)38/h10-13,19-20,23-27,48H,4-9,14-18,36H2,1-3H3,(H,43,51)(H,44,50)(H,45,52)(H,46,49)(H,54,55)(H4,37,38,41)(H4,39,40,42)/t20-,23-,24-,25-,26-,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281783
((S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylami...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C38H65N13O7/c1-5-22(4)30(35(57)48-27(31(40)53)19-21(2)3)50-33(55)28(20-23-12-14-24(52)15-13-23)49-34(56)29-11-8-18-51(29)36(58)26(10-7-17-46-38(43)44)47-32(54)25(39)9-6-16-45-37(41)42/h12-15,21-22,25-30,52H,5-11,16-20,39H2,1-4H3,(H2,40,53)(H,47,54)(H,48,57)(H,49,56)(H,50,55)(H4,41,42,45)(H4,43,44,46)/t22-,25+,26+,27+,28+,29+,30+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281780
((2S,5S)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guan...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O Show InChI InChI=1S/C32H60N12O7/c1-6-18(4)24(28(48)42-22(30(50)51)16-17(2)3)43-25(45)19(5)40-27(47)23-12-9-15-44(23)29(49)21(11-8-14-39-32(36)37)41-26(46)20(33)10-7-13-38-31(34)35/h17-24H,6-16,33H2,1-5H3,(H,40,47)(H,41,46)(H,42,48)(H,43,45)(H,50,51)(H4,34,35,38)(H4,36,37,39)/t18-,19+,20+,21+,22+,23+,24+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281790
(2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C35H58N12O8/c1-4-19(2)27(31(52)43-20(3)33(54)55)46-29(50)25(18-21-11-13-22(48)14-12-21)45-30(51)26-10-7-17-47(26)32(53)24(9-6-16-42-35(39)40)44-28(49)23(36)8-5-15-41-34(37)38/h11-14,19-20,23-27,48H,4-10,15-18,36H2,1-3H3,(H,43,52)(H,44,49)(H,45,51)(H,46,50)(H,54,55)(H4,37,38,41)(H4,39,40,42)/t19-,20+,23+,24+,25+,26+,27+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281789
((S)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidin...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C29H54N12O7/c1-5-15(2)21(25(45)38-17(4)27(47)48)40-22(42)16(3)37-24(44)20-11-8-14-41(20)26(46)19(10-7-13-36-29(33)34)39-23(43)18(30)9-6-12-35-28(31)32/h15-21H,5-14,30H2,1-4H3,(H,37,44)(H,38,45)(H,39,43)(H,40,42)(H,47,48)(H4,31,32,35)(H4,33,34,36)/t15-,16+,17+,18+,19+,20+,21+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
Neurotensin receptor type 1
(MOUSE) | BDBM50281792
((S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylami...)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C32H54N12O6/c1-3-18(2)25(26(34)46)43-28(48)23(17-19-10-12-20(45)13-11-19)42-29(49)24-9-6-16-44(24)30(50)22(8-5-15-40-32(37)38)41-27(47)21(33)7-4-14-39-31(35)36/h10-13,18,21-25,45H,3-9,14-17,33H2,1-2H3,(H2,34,46)(H,41,47)(H,42,49)(H,43,48)(H4,35,36,39)(H4,37,38,40)/t18-,21+,22+,23+,24+,25+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) |
Bioorg Med Chem Lett 3: 949-952 (1993)
Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX |
More data for this
Ligand-Target Pair | |
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