| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50240609 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36168 (CHEMBL646980) |
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| IC50 | 110±n/a nM |
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| Citation |  Cho, N; Kubo, K; Furuya, S; Sugiura, Y; Yasuma, T; Kohara, Y; Ojima, M; Inada, Y; Nishikawa, K; Naka, T A new class of diacidic nonpeptide angiotensin II receptor antagonists Bioorg Med Chem Lett4:35-40 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41107.81 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_36779 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
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| BDBM50240609 |
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| n/a |
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| Name | BDBM50240609 |
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| Synonyms: | 2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid(CV-11974) | 2-Ethoxy-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid | 2-ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid | CANDESARTAN | CHEMBL1016 | CV-11974 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N6O3 |
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| Mol. Mass. | 440.454 |
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| SMILES | CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |
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| Structure | 
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