| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50283048 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210264 |
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| IC50 | 24±n/a nM |
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| Citation |  Vlattas, I; Dellureficio, J; Cohen, DS; Lee, W; Clarke, F; Dotson, R; Mathis, J; Zoganas, H Thia-prostanoid analogs with combined thromboxane receptor antagonist/thromboxane synthase inhibitor activities. Synthesis and pharmacological evaluation Bioorg Med Chem Lett4:2067-2072 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50283048 |
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| n/a |
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| Name | BDBM50283048 |
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| Synonyms: | (Z)-7-[(2S,3S,4R)-4-(Biphenyl-4-ylmethoxy)-1,1-dioxo-2-pyridin-3-yl-tetrahydro-1lambda*6*-thiophen-3-yl]-hept-4-enoic acid | CHEMBL292740 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31NO5S |
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| Mol. Mass. | 505.625 |
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| SMILES | OC(=O)CC\C=C/CC[C@H]1[C@H](CS(=O)(=O)[C@@H]1c1cccnc1)OCc1ccc(cc1)-c1ccccc1 |
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| Structure | 
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