Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003780 (4-(3-Pyridin-3-yl-propyl)-8-(toluene-4-sulfonylami...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003792 (8-(4-Fluoro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003784 (8-(4-Chloro-benzenesulfonylamino)-4-[3-(4-methyl-p...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM25400 ((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003803 (8-(Naphthalene-2-sulfonylamino)-4-(3-pyridin-3-yl-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003801 (4-(3-Pyridin-3-yl-propyl)-8-(4-trifluoromethyl-ben...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003781 (CHEMBL341686 | [5-(4-Chloro-benzenesulfonylamino)-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation | J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthase | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of the compound against thromboxane synthase | Bioorg Med Chem Lett 4: 2073-2076 (1994) Article DOI: 10.1016/S0960-894X(01)80104-9 BindingDB Entry DOI: 10.7270/Q2C53KS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003797 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation | J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003795 (5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars | DrugBank PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003798 (8-(4-Chloro-benzenesulfonylamino)-4-(3-imidazol-1-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003799 (8-(4-Chloro-benzenesulfonylamino)-2-methyl-4-(3-py...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003800 (8-(4-Methoxy-benzenesulfonylamino)-4-(3-pyridin-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003796 (8-(4-Chloro-benzenesulfonylamino)-4-[3-(1-oxy-pyri...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003797 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50025953 (6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid | CGS-1...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthase | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003795 (5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars | DrugBank Article | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of the compound against thromboxane synthase | Bioorg Med Chem Lett 4: 2073-2076 (1994) Article DOI: 10.1016/S0960-894X(01)80104-9 BindingDB Entry DOI: 10.7270/Q2C53KS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50046312 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation | J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003789 (8-(4-Methanesulfonyl-benzenesulfonylamino)-4-(3-py...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003794 (8-(4-Azido-benzenesulfonylamino)-4-(3-pyridin-3-yl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283051 ((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of the compound against thromboxane synthase | Bioorg Med Chem Lett 4: 2073-2076 (1994) Article DOI: 10.1016/S0960-894X(01)80104-9 BindingDB Entry DOI: 10.7270/Q2C53KS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283051 ((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition against thromboxane synthase | Bioorg Med Chem Lett 4: 2073-2076 (1994) Article DOI: 10.1016/S0960-894X(01)80104-9 BindingDB Entry DOI: 10.7270/Q2C53KS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50046311 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation | J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003787 (4-Chloro-N-{8-pyridin-3-yl-5-[2-(5H-tetrazol-5-yl)...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50046309 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation | J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50009552 (2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50118810 ((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003790 (CHEMBL136880 | Potassium; 8-(4-chloro-benzenesulfo...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003804 (7-(4-Chloro-benzenesulfonylamino)-3-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280267 (CHEMBL295121 | [3-[3-(4-Chloro-benzenesulfonylamin...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparation | Bioorg Med Chem Lett 2: 1623-1626 (1992) Article DOI: 10.1016/S0960-894X(00)80443-6 BindingDB Entry DOI: 10.7270/Q26M36QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280268 (3-[3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-5-(...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparation | Bioorg Med Chem Lett 2: 1623-1626 (1992) Article DOI: 10.1016/S0960-894X(00)80443-6 BindingDB Entry DOI: 10.7270/Q26M36QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003793 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283046 ((Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human platelets | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283042 ((Z)-7-[(2S,3S,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthase | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50283049 ((Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human platelets | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283046 ((Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthase | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50046310 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation | J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283046 ((Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of thromboxane synthase | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50009535 ((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280260 (7-{4-[3-(4-Chloro-benzenesulfonylamino)-propyl]-py...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme | Bioorg Med Chem Lett 2: 1619-1622 (1992) Article DOI: 10.1016/S0960-894X(00)80442-4 BindingDB Entry DOI: 10.7270/Q2BC3ZF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280264 (3-[5-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-2-(...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparation | Bioorg Med Chem Lett 2: 1623-1626 (1992) Article DOI: 10.1016/S0960-894X(00)80443-6 BindingDB Entry DOI: 10.7270/Q26M36QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50283051 ((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of the compound against thromboxane synthase | Bioorg Med Chem Lett 4: 2073-2076 (1994) Article DOI: 10.1016/S0960-894X(01)80104-9 BindingDB Entry DOI: 10.7270/Q2C53KS7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50009543 (2-{6-Amino-2-[2-(5,6,7,8-tetrahydro-naphthalen-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptor | J Med Chem 34: 2570-9 (1991) BindingDB Entry DOI: 10.7270/Q2BZ66NN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003791 (CHEMBL343535 | [5-(4-Chloro-benzenesulfonylamino)-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description In vitro inhibition of Thromboxane A2 synthase | J Med Chem 35: 4373-83 (1992) BindingDB Entry DOI: 10.7270/Q2F47N3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50283047 ((Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-1,1-dio...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human platelets | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human platelets | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair |
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