| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50285690 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_79978 (CHEMBL874137) |
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| Ki | 20±n/a nM |
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| Citation |  Randad, RS; Lubkowska, L; Bujacz, A; Naik, RH; Gulnik, SV; Yu, B; Silva, A; Munshi, S; Lynch, TM; Clanton, DJ; Bhat, TN; Erickson, JW Structure-based design of achiral anthranilamides as P2/P2′ surrogates for symmetry-based HIV protease inhibitors: design, synthesis, X-ray structure, enzyme inhibition and antiviral activity Bioorg Med Chem Lett5:2557-2562 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50285690 |
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| n/a |
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| Name | BDBM50285690 |
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| Synonyms: | Anthranilamide derivative | CHEMBL87309 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H46N4O10 |
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| Mol. Mass. | 838.8996 |
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| SMILES | O[C@@H]([C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1NC(=O)OCc1ccccc1)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1NC(=O)OCc1ccccc1 |
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| Structure | 
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