| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50287045 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_136064 |
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| IC50 | 2±n/a nM |
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| Citation |  Archer, S; Glick, SD; Maisonneuve, IM; Bidlack, JM; Xu, JY; Teitler, M; Sebastian, A; El-Hamouly, W; Hutchinson, I Suppression of morphine and cocaine self-administration in rats by a mixed mu antagonist-kappa agonist (N-CBM-TAMO) and a long-acting selective D1 antagonist (AS-300) Bioorg Med Chem Lett6:1139-1144 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45038.37 |
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| Organism: | CALF |
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| Description: | OPIATE Mu 2 0 CALF::P79350 |
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| Residue: | 401 |
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| Sequence: | MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLC
PSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALA
TSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALD
LRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVF
IFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIH
IYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSST
IEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
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| BDBM50287045 |
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| n/a |
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| Name | BDBM50287045 |
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| Synonyms: | CHEMBL14680 | N-CBM-TAMO |
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| Type | Small organic molecule |
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| Emp. Form. | C46H54N4O8S2 |
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| Mol. Mass. | 855.073 |
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| SMILES | Oc1ccc2C[C@H]3N(CC4CCC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)CSSCC(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CCC1)CC[C@@]235)ccc4O |
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| Structure | 
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