| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-1 |
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| Ligand | BDBM50063703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_92228 |
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| IC50 | 9890±n/a nM |
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| Citation |  Gilmore, JL; Hays, SJ; Caprathe, BW; Lee, C; Emmerling, MR; Michael, W; Jaen, JC Synthesis and evaluation of 2-aryl-4H-3,1-benzoxazin-4-ones as C1r serine protease inhibitors Bioorg Med Chem Lett6:679-682 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-1 |
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| Name: | Kallikrein-1 |
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| Synonyms: | KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein |
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| Type: | Enzyme |
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| Mol. Mass.: | 28874.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06870 |
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| Residue: | 262 |
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| Sequence: | MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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| BDBM50063703 |
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| n/a |
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| Name | BDBM50063703 |
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| Synonyms: | 2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEMBL10378 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H8INO2 |
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| Mol. Mass. | 349.1233 |
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| SMILES | Ic1ccccc1-c1nc2ccccc2c(=O)o1 |
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| Structure | 
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