Ki Summary

Reaction Details

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Target

Beta-2 adrenergic receptor

Ligand

BDBM50002133

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_38464

630±n/a nM

Citation

Sher, PM; Mathur, A; Fisher, LG; Wu, G; Skwish, S; Michel, IM; Seiler, SM; Dickinson, KE Carboxyl-promoted enhancement of selectivity for the β₃ adrenergic receptor. Negative charge of the sulfonic acid BMS-187413 introduces-β₃ binding selectivity Bioorg Med Chem Lett7:1583-1588 (1997) Article

More Info.:

Get all data from this article, Assay Method

Beta-2 adrenergic receptor

Name:

Beta-2 adrenergic receptor

Synonyms:

Type:

n/a

Mol. Mass.:

46461.69

Organism:

Homo sapiens (Human)

Description:

P07550

Residue:

413

Sequence:

MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL

BDBM50002133

n/a

Name

BDBM50002133

Synonyms:

(+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)phenoxy)acetic acid | (4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (4-{2-[(R)-2-((R)-3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (BRL 37,344)(4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (R*, R*) (4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | 2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)phenoxy)acetic acid | BRL-37344 | CHEMBL284782

Type

Small organic molecule

Emp. Form.

C19H22ClNO4

Mol. Mass.

363.835

SMILES

C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1

Structure