| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50290025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58934 |
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| Ki | 8.4±n/a nM |
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| Citation |  Haworth, KE; Harrison, T; Kulagowski, JJ; Leeson, PD; Owens, AP; Ridgill, MP; Teall, MR; Fielding, M; Chapman, K; Emms, F; Marwood, R; Patel, S; Moss, KL 4-Heterocyclyl tetrahydropyridines as selective ligands for the human dopamine D4 receptor Bioorg Med Chem Lett7:2211-2216 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50290025 |
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| n/a |
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| Name | BDBM50290025 |
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| Synonyms: | 5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-benzooxazole | CHEMBL71208 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16Cl2N2O |
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| Mol. Mass. | 359.249 |
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| SMILES | Clc1ccc(CN2CCC(=CC2)c2nc3cc(Cl)ccc3o2)cc1 |c:9| |
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| Structure | 
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