| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
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| Ligand | BDBM50290662 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_196638 (CHEMBL800751) |
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| Ki | >1000±n/a nM |
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| Citation |  Farmer, LJ; Zhi, L; Jeong, S; Kallel, EA; Croston, G; Flatten, KS; Heyman, RA; Nadzan, AM Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands Bioorg Med Chem Lett7:2747-2752 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-beta |
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| Name: | Retinoic acid receptor RXR-beta |
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| Synonyms: | NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56932.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_39045 |
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| Residue: | 533 |
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| Sequence: | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
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| BDBM50290662 |
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| n/a |
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| Name | BDBM50290662 |
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| Synonyms: | (2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopentyl]-penta-2,4-dienoic acid | CHEMBL92394 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H36O2 |
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| Mol. Mass. | 380.5628 |
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| SMILES | C\C(\C=C\C1(CCCC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O |
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| Structure | 
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