| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50098785 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_214951 |
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| IC50 | 200±n/a nM |
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| Citation |  Burgess, LE; Koch, K; Cooper, K; Biggers, MS; Ramchandani, M; Smitrovich, JH; Gilbert, EJ; Bruns, MJ; Mather, RJ; Donovan, CB; Hanson, DC The SAR of UK-78,282: A novel blocker of human T cell Kv1.3 potassium channels Bioorg Med Chem Lett7:1047-1052 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63835.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1513935 |
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| Residue: | 575 |
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| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50098785 |
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| n/a |
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| Name | BDBM50098785 |
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| Synonyms: | 4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-propyl]-piperidine | CHEMBL9653 | UK-78282 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H35NO2 |
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| Mol. Mass. | 429.5937 |
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| SMILES | COc1ccc(CCCN2CCC(COC(c3ccccc3)c3ccccc3)CC2)cc1 |
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| Structure | 
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