Compile Data Set for Download or QSAR

Found 299 hits with Last Name = 'cooper' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-leukotriene D4 (LTD4) from receptor in guinea pig lung membranes				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C34H29ClN6O3/c1-4-44-34(43)31-30(24-9-5-6-10-25(24)35)29(33(42)40-28-11-7-8-17-37-28)20(2)38-32(31)22-12-14-23(15-13-22)41-21(3)39-26-19-36-18-16-27(26)41/h5-19,29-30H,4H2,1-3H3,(H,37,40,42)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ligand from platelet activating factor (PAF) receptor in rabbit platelets				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284689 (7-Chloro-2-((E)-2-{3-[4-(2-methyl-imidazo[4,5-c]py...) Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)cc1 Show InChI InChI=1S/C31H23ClN4O/c1-21-34-30-19-33-16-15-31(30)36(21)27-11-13-28(14-12-27)37-20-23-4-2-3-22(17-23)5-9-26-10-7-24-6-8-25(32)18-29(24)35-26/h2-19H,20H2,1H3/b9-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-LTD4 from receptor in guinea pig lung membranes				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50284689 (7-Chloro-2-((E)-2-{3-[4-(2-methyl-imidazo[4,5-c]py...) Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)cc1 Show InChI InChI=1S/C31H23ClN4O/c1-21-34-30-19-33-16-15-31(30)36(21)27-11-13-28(14-12-27)37-20-23-4-2-3-22(17-23)5-9-26-10-7-24-6-8-25(32)18-29(24)35-26/h2-19H,20H2,1H3/b9-5+	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ligand from platelet activating factor (PAF) receptor in rabbit platelets				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50284691 (2-(2-{3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-yl)-p...) Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccccc4n3)c2)cc1 Show InChI InChI=1S/C31H24N4O/c1-22-33-30-20-32-18-17-31(30)35(22)27-13-15-28(16-14-27)36-21-24-6-4-5-23(19-24)9-11-26-12-10-25-7-2-3-8-29(25)34-26/h2-20H,21H2,1H3/b11-9+	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ligand from platelet activating factor (PAF) receptor in rabbit platelets				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284690 (1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2-yl)-vinyl]...) Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3nc4cc(F)ccc4s3)c2)cc1 Show InChI InChI=1S/C29H21FN4OS/c1-19-32-26-17-31-14-13-27(26)34(19)23-7-9-24(10-8-23)35-18-21-4-2-3-20(15-21)5-12-29-33-25-16-22(30)6-11-28(25)36-29/h2-17H,18H2,1H3/b12-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-leukotriene D4 (LTD4) from receptor in guinea pig lung membranes				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50284690 (1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2-yl)-vinyl]...) Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3nc4cc(F)ccc4s3)c2)cc1 Show InChI InChI=1S/C29H21FN4OS/c1-19-32-26-17-31-14-13-27(26)34(19)23-7-9-24(10-8-23)35-18-21-4-2-3-20(15-21)5-12-29-33-25-16-22(30)6-11-28(25)36-29/h2-17H,18H2,1H3/b12-5+	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ligand from platelet activating factor (PAF) receptor in rabbit platelets				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284691 (2-(2-{3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-yl)-p...) Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccccc4n3)c2)cc1 Show InChI InChI=1S/C31H24N4O/c1-22-33-30-20-32-18-17-31(30)35(22)27-13-15-28(16-14-27)36-21-24-6-4-5-23(19-24)9-11-26-12-10-25-7-2-3-8-29(25)34-26/h2-20H,21H2,1H3/b11-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-leukotriene D4 (LTD4) from receptor in guinea pig lung membranes				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C34H29ClN6O3/c1-4-44-34(43)31-30(24-9-5-6-10-25(24)35)29(33(42)40-28-11-7-8-17-37-28)20(2)38-32(31)22-12-14-23(15-13-22)41-21(3)39-26-19-36-18-16-27(26)41/h5-19,29-30H,4H2,1-3H3,(H,37,40,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-leukotriene D4 (LTD4) from receptor in guinea pig lung membranes				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ligand from platelet activating factor (PAF) receptor in rabbit platelets				Bioorg Med Chem Lett 5: 1377-1382 (1995) Article DOI: 10.1016/0960-894X(95)00227-K BindingDB Entry DOI: 10.7270/Q2M045D5
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033236 (8,9-Dichloro-2-methyl-5-[4-(2-methyl-imidazo[4,5-c...) Show SMILES Cc1cn-2c(CC(=Nc3cc(Cl)c(Cl)cc-23)c2ccc(cc2)-n2c(C)nc3cnccc23)n1 |c:6| Show InChI InChI=1S/C25H18Cl2N6/c1-14-13-32-24-10-19(27)18(26)9-21(24)31-20(11-25(32)29-14)16-3-5-17(6-4-16)33-15(2)30-22-12-28-8-7-23(22)33/h3-10,12-13H,11H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033242 (3-Cyclohexyl-6-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2c(nn3CCCCN(c23)C(=O)C1)C1CCCCC1 |t:19| Show InChI InChI=1S/C29H31N7O/c1-19-31-24-18-30-14-13-25(24)36(19)22-11-9-20(10-12-22)23-17-26(37)34-15-5-6-16-35-29(34)28(32-23)27(33-35)21-7-3-2-4-8-21/h9-14,18,21H,2-8,15-17H2,1H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033213 (7,8-Dichloro-1-methyl-4-[4-(2-methyl-imidazo[4,5-c...) Show SMILES CN1c2cc(Cl)c(Cl)cc2CC(CC1=O)c1ccc(cc1)-n1c(C)nc2cnccc12 Show InChI InChI=1S/C24H20Cl2N4O/c1-14-28-21-13-27-8-7-22(21)30(14)18-5-3-15(4-6-18)16-9-17-10-19(25)20(26)12-23(17)29(2)24(31)11-16/h3-8,10,12-13,16H,9,11H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033211 (7,8-Dichloro-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(Cl)c(Cl)cc2NC(=S)C1 |t:19| Show InChI InChI=1S/C22H15Cl2N5S/c1-12-26-20-11-25-7-6-21(20)29(12)14-4-2-13(3-5-14)17-10-22(30)28-19-9-16(24)15(23)8-18(19)27-17/h2-9,11H,10H2,1H3,(H,28,30)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004622 (4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)OCCOC)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C32H31ClN4O5/c1-5-41-32(39)29-28(23-8-6-7-9-24(23)33)27(31(38)42-17-16-40-4)19(2)35-30(29)21-10-12-22(13-11-21)37-20(3)36-25-18-34-15-14-26(25)37/h6-15,18,27-28H,5,16-17H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033257 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1ccccc1 |c:4| Show InChI InChI=1S/C27H23N7O/c1-17-29-22-16-28-14-13-23(22)34(17)20-11-9-18(10-12-20)21-15-24(35)32(2)27-26(30-21)25(31-33(27)3)19-7-5-4-6-8-19/h4-14,16H,15H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033212 (7,8-Dichloro-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1Cc2cc(Cl)c(Cl)cc2NC(=O)C1 Show InChI InChI=1S/C23H18Cl2N4O/c1-13-27-21-12-26-7-6-22(21)29(13)17-4-2-14(3-5-17)15-8-16-9-18(24)19(25)11-20(16)28-23(30)10-15/h2-7,9,11-12,15H,8,10H2,1H3,(H,28,30)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033223 (7,8-Dimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(C)c(C)cc2NC(=S)C1 |t:19| Show InChI InChI=1S/C24H21N5S/c1-14-10-20-21(11-15(14)2)28-24(30)12-19(27-20)17-4-6-18(7-5-17)29-16(3)26-22-13-25-9-8-23(22)29/h4-11,13H,12H2,1-3H3,(H,28,30)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033240 (1-Methyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2c(NC(=O)C1)n(C)nc2-c1ccccc1 |t:19| Show InChI InChI=1S/C26H21N7O/c1-16-28-21-15-27-13-12-22(21)33(16)19-10-8-17(9-11-19)20-14-23(34)30-26-25(29-20)24(31-32(26)2)18-6-4-3-5-7-18/h3-13,15H,14H2,1-2H3,(H,30,34)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033238 (3-(4-Chloro-phenyl)-1,8-dimethyl-5-[4-(2-methyl-im...) Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1ccc(Cl)cc1 |c:4| Show InChI InChI=1S/C27H22ClN7O/c1-16-30-22-15-29-13-12-23(22)35(16)20-10-6-17(7-11-20)21-14-24(36)33(2)27-26(31-21)25(32-34(27)3)18-4-8-19(28)9-5-18/h4-13,15H,14H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033264 (3-Cyclohexyl-1,8-dimethyl-5-[4-(2-methyl-imidazo[4...) Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)C1CCCCC1 |c:4| Show InChI InChI=1S/C27H29N7O/c1-17-29-22-16-28-14-13-23(22)34(17)20-11-9-18(10-12-20)21-15-24(35)32(2)27-26(30-21)25(31-33(27)3)19-7-5-4-6-8-19/h9-14,16,19H,4-8,15H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033214 (7,8-Dimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(C)c(C)cc2NC(=O)C1 |t:19| Show InChI InChI=1S/C24H21N5O/c1-14-10-20-21(11-15(14)2)28-24(30)12-19(27-20)17-4-6-18(7-5-17)29-16(3)26-22-13-25-9-8-23(22)29/h4-11,13H,12H2,1-3H3,(H,28,30)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033260 (3-Isobutoxymethyl-1,8-dimethyl-5-[4-(2-methyl-imid...) Show SMILES CC(C)COCc1nn(C)c2N(C)C(=O)CC(=Nc12)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:16| Show InChI InChI=1S/C26H29N7O2/c1-16(2)14-35-15-22-25-26(32(5)30-22)31(4)24(34)12-20(29-25)18-6-8-19(9-7-18)33-17(3)28-21-13-27-11-10-23(21)33/h6-11,13,16H,12,14-15H2,1-5H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033206 (7,8-Dichloro-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(Cl)c(Cl)cc2NC(=O)C1 |t:19| Show InChI InChI=1S/C22H15Cl2N5O/c1-12-26-20-11-25-7-6-21(20)29(12)14-4-2-13(3-5-14)17-10-22(30)28-19-9-16(24)15(23)8-18(19)27-17/h2-9,11H,10H2,1H3,(H,28,30)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033234 (1,3-Dimethyl-7-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nn(C)c2N=C(CC(=O)Nc12)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:6| Show InChI InChI=1S/C21H19N7O/c1-12-20-21(27(3)26-12)24-16(10-19(29)25-20)14-4-6-15(7-5-14)28-13(2)23-17-11-22-9-8-18(17)28/h4-9,11H,10H2,1-3H3,(H,25,29)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033233 (8,9-Dichloro-1-methyl-5-[4-(2-methyl-imidazo[4,5-c...) Show SMILES Cc1cnc2CC(=Nc3cc(Cl)c(Cl)cc3-n12)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:6| Show InChI InChI=1S/C25H18Cl2N6/c1-14-12-29-25-11-20(31-21-9-18(26)19(27)10-24(21)32(14)25)16-3-5-17(6-4-16)33-15(2)30-22-13-28-8-7-23(22)33/h3-10,12-13H,11H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004615 (4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)OC(C)(C)C)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C33H33ClN4O4/c1-7-41-31(39)29-28(23-10-8-9-11-24(23)34)27(32(40)42-33(4,5)6)19(2)36-30(29)21-12-14-22(15-13-21)38-20(3)37-25-18-35-17-16-26(25)38/h8-18,27-28H,7H2,1-6H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033249 (5,7,9-Trimethyl-2-[4-(2-methyl-imidazo[4,5-c]pyrid...) Show SMILES CN1c2nc(C)cc(C)c2N=C(CC1=O)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:11| Show InChI InChI=1S/C24H22N6O/c1-14-11-15(2)26-24-23(14)28-19(12-22(31)29(24)4)17-5-7-18(8-6-17)30-16(3)27-20-13-25-10-9-21(20)30/h5-11,13H,12H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033229 (8,9-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(C)c(C)cc2-n2ccnc2C1 |t:19| Show InChI InChI=1S/C26H22N6/c1-16-12-22-25(13-17(16)2)31-11-10-28-26(31)14-21(30-22)19-4-6-20(7-5-19)32-18(3)29-23-15-27-9-8-24(23)32/h4-13,15H,14H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033245 (8-Bromo-5-methyl-2-[4-(2-methyl-imidazo[4,5-c]pyri...) Show SMILES CN1c2ncc(Br)cc2N=C(CC1=O)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:10| Show InChI InChI=1S/C22H17BrN6O/c1-13-26-19-12-24-8-7-20(19)29(13)16-5-3-14(4-6-16)17-10-21(30)28(2)22-18(27-17)9-15(23)11-25-22/h3-9,11-12H,10H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033255 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1cccs1 |c:4| Show InChI InChI=1S/C25H21N7OS/c1-15-27-19-14-26-11-10-20(19)32(15)17-8-6-16(7-9-17)18-13-22(33)30(2)25-24(28-18)23(29-31(25)3)21-5-4-12-34-21/h4-12,14H,13H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004630 (4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)OC)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C30H27ClN4O4/c1-5-39-30(37)27-26(21-8-6-7-9-22(21)31)25(29(36)38-4)17(2)33-28(27)19-10-12-20(13-11-19)35-18(3)34-23-16-32-15-14-24(23)35/h6-16,25-26H,5H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033232 (8,9-Dichloro-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(Cl)c(Cl)cc2-n2ccnc2C1 |t:19| Show InChI InChI=1S/C24H16Cl2N6/c1-14-29-21-13-27-7-6-22(21)32(14)16-4-2-15(3-5-16)19-12-24-28-8-9-31(24)23-11-18(26)17(25)10-20(23)30-19/h2-11,13H,12H2,1H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004617 (4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-pyridi...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-c1cccnc1C |t:5,7| Show InChI InChI=1S/C33H29ClN4O3/c1-4-41-33(40)30-29(25-10-5-6-12-26(25)34)28(32(39)38-27-13-7-8-18-36-27)21(3)37-31(30)23-16-14-22(15-17-23)24-11-9-19-35-20(24)2/h5-19,28-29H,4H2,1-3H3,(H,36,38,39)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033207 (7,8-Dimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(C)c(C)cc2N=C(N)C1 |t:19,30| Show InChI InChI=1S/C24H22N6/c1-14-10-20-21(11-15(14)2)29-24(25)12-19(28-20)17-4-6-18(7-5-17)30-16(3)27-22-13-26-9-8-23(22)30/h4-11,13H,12H2,1-3H3,(H2,25,29)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.				J Med Chem 38: 3514-23 (1995) BindingDB Entry DOI: 10.7270/Q2PK0GSS
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50215854 (CHEMBL301829) Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C34H29ClN6O3/c1-4-44-34(43)31-30(24-9-5-6-10-25(24)35)29(33(42)40-28-11-7-8-17-37-28)20(2)38-32(31)22-12-14-23(15-13-22)41-21(3)39-26-19-36-18-16-27(26)41/h5-19,29-30H,4H2,1-3H3,(H,37,40,42)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory effect on PAF induced platelets aggregation in rabbit				Bioorg Med Chem Lett 5: 3085-3090 (1995) Article DOI: 10.1016/0960-894X(95)00542-7 BindingDB Entry DOI: 10.7270/Q23F4PMW
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50215854 (CHEMBL301829) Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004637 (4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-c1c(C)nc2ccccn12 |t:5,7| Show InChI InChI=1S/C35H30ClN5O3/c1-4-44-35(43)31-30(25-11-5-6-12-26(25)36)29(34(42)40-27-13-7-9-19-37-27)21(2)39-32(31)23-15-17-24(18-16-23)33-22(3)38-28-14-8-10-20-41(28)33/h5-20,29-30H,4H2,1-3H3,(H,37,40,42)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033263 (8,9-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2cc(C)c(C)cc2-n2cnnc2C1 |t:19| Show InChI InChI=1S/C25H21N7/c1-15-10-21-24(11-16(15)2)31-14-27-30-25(31)12-20(29-21)18-4-6-19(7-5-18)32-17(3)28-22-13-26-9-8-23(22)32/h4-11,13-14H,12H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004650 (6-Methyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1OC(F)(F)F)C(=O)Nc1ccccn1)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C35H29F3N6O4/c1-4-47-34(46)31-30(24-9-5-6-10-27(24)48-35(36,37)38)29(33(45)43-28-11-7-8-17-40-28)20(2)41-32(31)22-12-14-23(15-13-22)44-21(3)42-25-19-39-18-16-26(25)44/h5-19,29-30H,4H2,1-3H3,(H,40,43,45)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50286206 ((R)-5-tert-Butylcarbamoyl-4-(2-chloro-phenyl)-6-me...) Show SMILES CCOC(=O)C1=C(COCCn2c(C)nc3ccccc23)N=C(C)C([C@H]1c1ccccc1Cl)C(=O)NC(C)(C)C |c:5,t:23| Show InChI InChI=1S/C31H37ClN4O4/c1-7-40-30(38)28-24(18-39-17-16-36-20(3)34-23-14-10-11-15-25(23)36)33-19(2)26(29(37)35-31(4,5)6)27(28)21-12-8-9-13-22(21)32/h8-15,26-27H,7,16-18H2,1-6H3,(H,35,37)/t26?,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory effect on PAF induced platelets aggregation in rabbit				Bioorg Med Chem Lett 5: 3085-3090 (1995) Article DOI: 10.1016/0960-894X(95)00542-7 BindingDB Entry DOI: 10.7270/Q23F4PMW
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50215854 (CHEMBL301829) Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033231 (1,8,9-Trimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyrid...) Show SMILES Cc1nnc2CC(=Nc3cc(C)c(C)cc3-n12)c1ccc(cc1)-n1c(C)nc2cnccc12 |c:6| Show InChI InChI=1S/C26H23N7/c1-15-11-22-25(12-16(15)2)33-18(4)30-31-26(33)13-21(29-22)19-5-7-20(8-6-19)32-17(3)28-23-14-27-10-9-24(23)32/h5-12,14H,13H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033251 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) Show SMILES CN1c2c(N=C(CC1=O)c1ccc(cc1)-n1c(C)nc3cnccc13)c(nn2C)-c1cccnc1 |c:4| Show InChI InChI=1S/C26H22N8O/c1-16-29-21-15-28-12-10-22(21)34(16)19-8-6-17(7-9-19)20-13-23(35)32(2)26-25(30-20)24(31-33(26)3)18-5-4-11-27-14-18/h4-12,14-15H,13H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50004616 (4-(2-Chloro-phenyl)-2-methyl-6-[4-(2-methyl-imidaz...) Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)OCc1ccccc1)c1ccc(cc1)-n1c(C)nc2cnccc12 |t:5,7| Show InChI InChI=1S/C36H31ClN4O4/c1-4-44-36(43)33-32(27-12-8-9-13-28(27)37)31(35(42)45-21-24-10-6-5-7-11-24)22(2)39-34(33)25-14-16-26(17-15-25)41-23(3)40-29-20-38-19-18-30(29)41/h5-20,31-32H,4,21H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033246 (5-Methyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) Show SMILES CN1c2ncc(cc2N=C(CC1=O)c1ccc(cc1)-n1c(C)nc2cnccc12)C(=O)N1CCOCC1 |c:9| Show InChI InChI=1S/C27H25N7O3/c1-17-30-23-16-28-8-7-24(23)34(17)20-5-3-18(4-6-20)21-14-25(35)32(2)26-22(31-21)13-19(15-29-26)27(36)33-9-11-37-12-10-33/h3-8,13,15-16H,9-12,14H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50033243 (1-Methyl-7-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) Show SMILES Cc1nc2cnccc2n1-c1ccc(cc1)C1=Nc2c(NC(=O)C1)c(nn2C)-c1ccccc1 |t:19| Show InChI InChI=1S/C26H21N7O/c1-16-28-21-15-27-13-12-22(21)33(16)19-10-8-17(9-11-19)20-14-23(34)30-25-24(18-6-4-3-5-7-18)31-32(2)26(25)29-20/h3-13,15H,14H2,1-2H3,(H,30,34)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets				J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Mus musculus)	BDBM50470788 (CHEMBL278386) Show SMILES COc1ccc(cc1O[C@@H]1CC2CCC1C2)-c1ccc(cc1)C(O)=O |TLB:8:9:15:13.12| Show InChI InChI=1S/C21H22O4/c1-24-18-9-8-16(14-4-6-15(7-5-14)21(22)23)12-20(18)25-19-11-13-2-3-17(19)10-13/h4-9,12-13,17,19H,2-3,10-11H2,1H3,(H,22,23)/t13?,17?,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]rolipram from mouse brain homogenates				J Med Chem 39: 120-5 (1996) Article DOI: 10.1021/jm9505066 BindingDB Entry DOI: 10.7270/Q20P12Q4
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Mus musculus)	BDBM50470784 (CHEMBL282934) Show SMILES COc1ccc(cc1O[C@H]1CC2CCC1C2)-c1ccc(cc1)C(O)=O |TLB:8:9:15:13.12| Show InChI InChI=1S/C21H22O4/c1-24-18-9-8-16(14-4-6-15(7-5-14)21(22)23)12-20(18)25-19-11-13-2-3-17(19)10-13/h4-9,12-13,17,19H,2-3,10-11H2,1H3,(H,22,23)/t13?,17?,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]rolipram from mouse brain homogenates				J Med Chem 39: 120-5 (1996) Article DOI: 10.1021/jm9505066 BindingDB Entry DOI: 10.7270/Q20P12Q4
					More data for this Ligand-Target Pair

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