| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50303162 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_594896 (CHEMBL1038947) |
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| Ki | 11.3±n/a nM |
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| Citation |  Bernotas, RC; Antane, SA; Lenicek, SE; Haydar, SN; Robichaud, AJ; Harrison, BL; Zhang, GM; Smith, D; Coupet, J; Schechter, LE 1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines are 5-HT(6) receptor ligands. Bioorg Med Chem Lett19:6935-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50303162 |
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| n/a |
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| Name | BDBM50303162 |
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| Synonyms: | 1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-5-yl)ethanone | CHEMBL571878 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20FN3O3S |
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| Mol. Mass. | 389.444 |
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| SMILES | CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1cccc(F)c1 |
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| Structure | 
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