BindingDB PrimarySearch

Found 20 hits with Last Name = 'antane' and Initial = 'sa'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303164 (1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303163 (1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)e...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300828 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303162 (1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsul...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300832 (CHEMBL578826 \| N,N-Dimethyl-N-{2-[3-(phenylsulfony...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303166 (2-(3-(3-chlorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303168 (2-(3-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303167 (2-(3-(m-tolylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-1-...) Show SMILES Cc1cccc(c1)S(=O)(=O)c1cn(CCN)c2cccnc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303161 (1-(1-(2-(dimethylamino)ethyl)-3-(phenylsulfonyl)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303165 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1cccc(F)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303159 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303160 (2-(5-chloro-3-(phenylsulfonyl)-1H-pyrrolo[3,2-b]py...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303158 (CHEMBL576312 \| N,N-dimethyl-2-(3-(phenylsulfonyl)-...) Show SMILES CN(C)CCn1cc(c2ncccc12)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303162 (1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsul...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303166 (2-(3-(3-chlorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303164 (1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303163 (1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)e...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303165 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1cccc(F)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	823	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonistic activity at human HT6 receptor expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300832 (CHEMBL578826 \| N,N-Dimethyl-N-{2-[3-(phenylsulfony...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300828 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.30	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair