| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50160366 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_611967 (CHEMBL1072174) |
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| Ki | 13.4±n/a nM |
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| Citation |  Badarau, E; Bugno, R; Suzenet, F; Bojarski, AJ; Finaru, AL; Guillaumet, G SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling. Bioorg Med Chem18:1958-67 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50160366 |
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| n/a |
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| Name | BDBM50160366 |
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| Synonyms: | (S)-6-(2,6-dimethylphenyl)-N,N-dimethylchroman-3-amine | CHEMBL367584 | [(S)-6-(2,6-Dimethyl-phenyl)-chroman-3-yl]-dimethyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23NO |
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| Mol. Mass. | 281.392 |
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| SMILES | CN(C)[C@@H]1COc2ccc(cc2C1)-c1c(C)cccc1C |
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| Structure | 
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