| Reaction Details |
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 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
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| Ligand | BDBM50129679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_623303 (CHEMBL1115226) |
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| Ki | 230±n/a nM |
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| Citation |  Grzywa, R; Sokol, AM; Sienczyk, M; Radziszewicz, M; Kosciolek, B; Carty, MP; Oleksyszyn, J New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13. Bioorg Med Chem18:2930-6 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytosol aminopeptidase |
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| Name: | Cytosol aminopeptidase |
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| Synonyms: | AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56171.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507539 |
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| Residue: | 519 |
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| Sequence: | MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD
KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN
IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS
GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI
EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD
LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
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| BDBM50129679 |
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| n/a |
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| Name | BDBM50129679 |
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| Synonyms: | (1-Amino-3-methyl-butyl)-phosphonic acid | 1-amino-3-methylbutylphosphonic acid | CHEMBL89318 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H14NO3P |
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| Mol. Mass. | 167.1433 |
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| SMILES | CC(C)CC(N)P(O)(O)=O |
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| Structure | 
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