| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-glucosidase A |
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| Ligand | BDBM50163440 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639185 (CHEMBL1168038) |
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| pH | 5±n/a |
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| IC50 | 367000±n/a nM |
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| Comments | extracted |
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| Citation |  Kato, A; Yamashita, Y; Nakagawa, S; Koike, Y; Adachi, I; Hollinshead, J; Nash, RJ; Ikeda, K; Asano, N 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem18:3790-4 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-glucosidase A |
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| Name: | Beta-glucosidase A |
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| Synonyms: | BGLS_CALSA | bglA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53484.21 |
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| Organism: | Caldocellum saccharolyticum |
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| Description: | ChEMBL_37437 |
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| Residue: | 455 |
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| Sequence: | MDMSFPKGFLWGAATASYQIEGAWNEDGKGESIWDRFTHQKRNILYGHNGDVACDHYHRF
EEDVSLMKELGLKAYRFSIAWTRIFPDGFGTVNQKGLEFYDRLINKLVENGIEPVVTLYH
WDLPQKLQDIGGWANPEIVNYYFDYAMLVINRYKDKVKKWITFNEPYCIAFLGYFHGIHA
PGIKDFKVAMDVVHSLMLSHFKVVKAVKENNIDVEVGITLNLTPVYLQTERLGYKVSEIE
REMVSLSSQLDNQLFLDPVLKGSYPQKLLDYLVQKDLLDSQKALSMQQEVKENFIFPDFL
GINYYTRAVRLYDENSSWIFPIRWEHPAGEYTEMGWEVFPQGLFDLLIWIKESYPQIPIY
ITENGAAYNDIVTEDGKVHDSKRIEYLKQHFEAARKAIENGVDLRGYFVWSLMDNFEWAM
GYTKRFGIIYVDYETQKRIKKDSFYFYQQYIKENS
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|
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| BDBM50163440 |
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| n/a |
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| Name | BDBM50163440 |
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| Synonyms: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | (2R,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol | 1-deoxygalactonojirimycin | CHEMBL110458 | D-galacto-1-Deoxynojirimycin | DGJ |
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| Type | Small organic molecule |
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| Emp. Form. | C6H13NO4 |
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| Mol. Mass. | 163.1717 |
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| SMILES | OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
|
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