| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-galactosidase |
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| Ligand | BDBM50241865 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639187 (CHEMBL1168040) |
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| pH | 6.5±n/a |
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| IC50 | 780±n/a nM |
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| Comments | extracted |
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| Citation |  Kato, A; Yamashita, Y; Nakagawa, S; Koike, Y; Adachi, I; Hollinshead, J; Nash, RJ; Ikeda, K; Asano, N 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem18:3790-4 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-galactosidase |
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| Name: | Alpha-galactosidase |
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| Synonyms: | α-galactosidase | AGAL_COFAR | Alpha-galactosidase |
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| Type: | Protein |
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| Mol. Mass.: | 41306.82 |
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| Organism: | Coffea arabica (Coffee beans) |
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| Description: | n/a |
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| Residue: | 378 |
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| Sequence: | MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGY
KYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTM
PGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWG
EEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGM
TTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYG
DLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQ
ISAAVDAHDSKMYVLTPQ
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| BDBM50241865 |
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| n/a |
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| Name | BDBM50241865 |
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| Synonyms: | 2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine | CHEMBL469844 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H13NO4 |
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| Mol. Mass. | 163.1717 |
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| SMILES | OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| |
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| Structure | 
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