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TargetAlpha-galactosidase
LigandBDBM50320826
Substrate/Competitorn/a
Meas. Tech.ChEMBL_639187 (CHEMBL1168040)
pH6.5±n/a
IC50 1200±n/a nM
Commentsextracted
Citation Kato, AYamashita, YNakagawa, SKoike, YAdachi, IHollinshead, JNash, RJIkeda, KAsano, N 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem18:3790-4 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-galactosidase
Name:Alpha-galactosidase
Synonyms:α-galactosidase | AGAL_COFAR | Alpha-galactosidase
Type:Protein
Mol. Mass.:41306.82
Organism:Coffea arabica (Coffee beans)
Description:n/a
Residue:378
Sequence:
MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGY
KYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTM
PGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWG
EEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGM
TTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYG
DLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQ
ISAAVDAHDSKMYVLTPQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50320826
n/a
NameBDBM50320826
Synonyms:CHEMBL1163255 | beta-1-C-Butyl-1-deoxygalactonojirimycin
TypeSmall organic molecule
Emp. Form.C11H23NO3
Mol. Mass.217.3052
SMILESCCCC[C@@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@H]1C |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: