| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50416460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_644140 (CHEMBL1212039) |
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| Ki | 0.631±n/a nM |
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| Citation |  Biagetti, M; Leslie, CP; Mazzali, A; Seri, C; Pizzi, DA; Bentley, J; Genski, T; Di Fabio, R; Zonzini, L; Caberlotto, L Synthesis and structure-activity relationship of N-(3-azabicyclo[3.1.0]hex-6-ylmethyl)-5-(2-pyridinyl)-1,3-thiazol-2-amines derivatives as NPY Y5 antagonists. Bioorg Med Chem Lett20:4741-4 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 50746.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15761 |
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| Residue: | 445 |
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| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
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| BDBM50416460 |
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| n/a |
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| Name | BDBM50416460 |
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| Synonyms: | CHEMBL1209345 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20F2N4S |
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| Mol. Mass. | 398.472 |
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| SMILES | Fc1cc(F)cc(CN2C[C@H]3[C@@H](CNc4nc(cs4)-c4ccccn4)[C@H]3C2)c1 |r| |
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| Structure | 
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