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TargetRetinoic acid receptor RXR-alpha
LigandBDBM50157304
Substrate/Competitorn/a
Meas. Tech.ChEMBL_649615 (CHEMBL1219313)
EC50 11800±n/a nM
Citation Kotani, H; Tanabe, H; Mizukami, H; Makishima, M; Inoue, M Identification of a naturally occurring rexinoid, honokiol, that activates the retinoid X receptor. J Nat Prod73:1332-6 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Retinoic acid receptor RXR-alpha
Name:Retinoic acid receptor RXR-alpha
Synonyms:NR2B1 | Nuclear receptor subfamily 2 group B member 1 | Nuclear receptor subfamily 4 group A member 2 | Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha | RXRA | RXRA_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoid X receptor alpha | Retinoid receptor
Type:PROTEIN
Mol. Mass.:50820.38
Organism:Homo sapiens (Human)
Description:ChEMBL_1456363
Residue:462
Sequence:
MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
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  Blast E-value cutoff:
BDBM50157304
n/a
NameBDBM50157304
Synonyms:3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-diallylbiphenyl-2,4'-diol | 5,3''-Diallyl-biphenyl-2,4''-diol | 5,3'-diallyl-biphenyl-2,4'-diol | CHEMBL16901 | HONOKIOL | Honokiol, HO | cid_72303
TypeSmall organic molecule
Emp. Form.C18H18O2
Mol. Mass.266.3343
SMILESOc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O
Structure
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