| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoamine transporters; serotonin & dopamine |
|---|
| Ligand | BDBM50327861 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_664948 |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Xu R; Hong J; Morse CL; Pike VW Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography. J Med Chem 53:7035-47 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoamine transporters; serotonin & dopamine |
|---|
| Name: | Monoamine transporters; serotonin & dopamine |
|---|
| Synonyms: | DA transporter | DAT | DAT1 | Dopamine transporter (DAT) | Dopamine transporter protein (DAT) | SLC6A3 | Sodium-dependent dopamine transporter (DAT) | Solute carrier family 6 member 3 |
|---|
| Type: | Multi-pass membrane protein |
|---|
| Mol. Mass.: | 68497.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q01959 |
|---|
| Residue: | 620 |
|---|
| Sequence: | MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDR
ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL
GQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHC
NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQL
TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV
DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS
GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI
DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA
GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI
VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD
RELVDRGEVRQFTLRHWLKV
|
|
|
|---|
| BDBM50327861 |
|---|
| n/a |
|---|
| Name | BDBM50327861 |
|---|
| Synonyms: | (1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate | CHEMBL1258452 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H28N2O3 |
|---|
| Mol. Mass. | 320.4265 |
|---|
| SMILES | CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
