Reaction Details |
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Target | Bcl-2-related protein A1 |
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Ligand | BDBM50313365 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_676082 (CHEMBL1273076) |
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IC50 | 1700±n/a nM |
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Citation | Cashman, JR; MacDonald, M; Ghirmai, S; Okolotowicz, KJ; Sergienko, E; Brown, B; Garcia, X; Zhai, D; Dahl, R; Reed, JC Inhibition of Bfl-1 with N-aryl maleimides. Bioorg Med Chem Lett20:6560-4 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Bcl-2-related protein A1 |
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Name: | Bcl-2-related protein A1 |
Synonyms: | B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS |
Type: | Apoptosis regulator protein |
Mol. Mass.: | 20130.01 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 175 |
Sequence: | MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
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BDBM50313365 |
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n/a |
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Name | BDBM50313365 |
Synonyms: | (2R,3R,4S,5S,6R)-2-(3-(4-ethylbenzyl)-4-methylbenzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol | CHEMBL1085188 |
Type | Small organic molecule |
Emp. Form. | C23H30O6 |
Mol. Mass. | 402.4807 |
SMILES | CCc1ccc(Cc2cc(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2C)cc1 |r| |
Structure |
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