| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50331430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_687185 (CHEMBL1291810) |
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| IC50 | 1300±n/a nM |
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| Citation |  Haffner, CD; Thomson, SA; Guo, Y; Schaller, LT; Boggs, S; Dickerson, S; Gobel, J; Gillie, D; Condreay, JP N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1. Bioorg Med Chem Lett20:6983-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63835.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1513935 |
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| Residue: | 575 |
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| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50331430 |
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| n/a |
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| Name | BDBM50331430 |
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| Synonyms: | 1-{3-[(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-phenyl-amino]-propyl}-3-phenyl-urea | CHEMBL1290168 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4O3S |
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| Mol. Mass. | 434.511 |
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| SMILES | O=C(NCCCN(C1=NS(=O)(=O)c2ccccc12)c1ccccc1)Nc1ccccc1 |t:7| |
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| Structure | 
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