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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50332880 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_694005 (CHEMBL1636581) | ||
| Ki | 182.1±n/a nM | ||
| Citation |  Silvestri, R; Ligresti, A; La Regina, G; Piscitelli, F; Gatti, V; Lavecchia, A; Brizzi, A; Pasquini, S; Allarà, M; Fantini, N; Carai, MA; Bigogno, C; Rozio, MG; Sinisi, R; Novellino, E; Colombo, G; Di Marzo, V; Dondio, G; Corelli, F Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. Eur J Med Chem45:5878-86 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
| ||
| BDBM50332880 | |||
| n/a | |||
| Name | BDBM50332880 | ||
| Synonyms: | 1-(2,4-Dichlorophenyl)-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methyl-N-pentyl-1H-pyrazole-3-carboxamide | CHEMBL1631168 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H26Cl2N4O | ||
| Mol. Mass. | 433.374 | ||
| SMILES | CCCCCNC(=O)c1nn(c(c1C)-n1c(C)ccc1C)-c1ccc(Cl)cc1Cl |(21.54,-1.2,;20.8,.15,;19.27,.19,;18.54,1.55,;16.99,1.58,;16.26,2.92,;14.72,2.97,;13.99,4.3,;13.82,1.72,;14.3,.28,;13.07,-.64,;11.81,.25,;12.28,1.72,;11.37,2.97,;10.35,-.23,;9.89,-1.69,;10.68,-2.81,;8.34,-1.7,;7.86,-.24,;9.08,.67,;9.07,2.21,;13.09,-2.18,;11.76,-2.97,;11.78,-4.51,;13.12,-5.27,;13.13,-6.81,;14.45,-4.49,;14.43,-2.94,;15.76,-2.15,)| | ||
| Structure | 
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