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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50332894 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_694005 (CHEMBL1636581) | ||
| Ki | 104.7±n/a nM | ||
| Citation |  Silvestri, R; Ligresti, A; La Regina, G; Piscitelli, F; Gatti, V; Lavecchia, A; Brizzi, A; Pasquini, S; Allarà, M; Fantini, N; Carai, MA; Bigogno, C; Rozio, MG; Sinisi, R; Novellino, E; Colombo, G; Di Marzo, V; Dondio, G; Corelli, F Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. Eur J Med Chem45:5878-86 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
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| BDBM50332894 | |||
| n/a | |||
| Name | BDBM50332894 | ||
| Synonyms: | 1-(2,4-Dichlorophenyl)-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methyl-N-(octan-2-yl)-1H-pyrazole-3-carboxamide | CHEMBL1631300 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H32Cl2N4O | ||
| Mol. Mass. | 475.454 | ||
| SMILES | CCCCCCC(C)NC(=O)c1nn(c(c1C)-n1c(C)ccc1C)-c1ccc(Cl)cc1Cl |(29.45,-13.96,;28.68,-12.63,;27.14,-12.64,;26.36,-11.31,;24.82,-11.32,;24.04,-9.99,;22.5,-9.99,;21.74,-11.33,;21.73,-8.67,;20.18,-8.67,;19.42,-7.35,;19.41,-10.03,;19.82,-11.5,;18.55,-12.35,;17.35,-11.39,;17.89,-9.95,;17.06,-8.65,;15.82,-11.31,;14.89,-10.07,;15.34,-8.6,;13.44,-10.56,;13.45,-12.09,;14.92,-12.56,;15.41,-14.02,;18.55,-13.9,;17.22,-14.67,;17.22,-16.21,;18.55,-16.98,;18.55,-18.52,;19.89,-16.21,;19.88,-14.66,;21.23,-13.88,)| | ||
| Structure | 
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