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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50332893 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_694006 (CHEMBL1636582) | ||
| Ki | 133.5±n/a nM | ||
| Citation |  Silvestri, R; Ligresti, A; La Regina, G; Piscitelli, F; Gatti, V; Lavecchia, A; Brizzi, A; Pasquini, S; Allarà, M; Fantini, N; Carai, MA; Bigogno, C; Rozio, MG; Sinisi, R; Novellino, E; Colombo, G; Di Marzo, V; Dondio, G; Corelli, F Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. Eur J Med Chem45:5878-86 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
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| BDBM50332893 | |||
| n/a | |||
| Name | BDBM50332893 | ||
| Synonyms: | 1-(2,4-Dichlorophenyl)-5-(2,5-dimethyl-1H-pyrrol-1-yl)-N-(3,3-dimethylbutyl)-4-methyl-1H-pyrazole-3-carboxamide | CHEMBL1631299 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H28Cl2N4O | ||
| Mol. Mass. | 447.401 | ||
| SMILES | Cc1ccc(C)n1-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NCCC(C)(C)C |(14.88,-7.03,;14.36,-8.48,;12.9,-8.91,;12.84,-10.43,;14.29,-10.96,;14.71,-12.45,;15.24,-9.76,;16.78,-9.82,;17.32,-8.39,;16.49,-7.08,;18.84,-8.46,;19.26,-9.93,;17.98,-10.79,;17.98,-12.33,;16.65,-13.11,;16.65,-14.65,;17.98,-15.42,;17.98,-16.96,;19.32,-14.65,;19.31,-13.1,;20.66,-12.32,;19.67,-7.14,;18.95,-5.79,;21.21,-7.19,;21.93,-8.55,;23.47,-8.6,;24.2,-9.95,;23.39,-11.26,;25.74,-10,;24.74,-11.39,)| | ||
| Structure | 
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