| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
|---|
| Ligand | BDBM50336508 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_723554 (CHEMBL1676794) |
|---|
| Ki | 120000±n/a nM |
|---|
| Citation |  Ishii, Y; Eto, M; Mano, Y; Tateda, K; Yamaguchi, K In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother54:3625-9 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metallo-beta-lactamase VIM-2 |
|---|
| Name: | Metallo-beta-lactamase VIM-2 |
|---|
| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 28318.00 |
|---|
| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
|---|
| Description: | n/a |
|---|
| Residue: | 266 |
|---|
| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
|
|
|
|---|
| BDBM50336508 |
|---|
| n/a |
|---|
| Name | BDBM50336508 |
|---|
| Synonyms: | CHEMBL1673299 | sodium 2,3-diethylmaleate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H10O4 |
|---|
| Mol. Mass. | 170.1637 |
|---|
| SMILES | CC\C(C([O-])=O)=C(/CC)C([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
