| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50336509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_723551 (CHEMBL1676791) |
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| Ki | 180±n/a nM |
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| Citation |  Ishii, Y; Eto, M; Mano, Y; Tateda, K; Yamaguchi, K In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother54:3625-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27125.88 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_27368096 |
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| Residue: | 246 |
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| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
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| BDBM50336509 |
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| n/a |
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| Name | BDBM50336509 |
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| Synonyms: | CHEMBL116455 | Mercapto-acetic acid | Mercaptoacetic acid | SULFANYLACETIC ACID |
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| Type | Small organic molecule |
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| Emp. Form. | C2H4O2S |
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| Mol. Mass. | 92.117 |
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| SMILES | OC(=O)CS |
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| Structure | 
|
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